Could a common Alzheimer's drug sharpen minds in down syndrome?
NCT ID NCT07531940
First seen Apr 23, 2026 · Last updated May 14, 2026 · Updated 2 times
Summary
This early-stage study will test whether higher-than-normal doses of memantine, a drug already approved for Alzheimer's, are safe and might improve memory and thinking in 25 adolescents and young adults with Down syndrome. Participants will try three different doses to find the best balance of safety and potential benefit. The goal is to gather enough information to plan a larger, more definitive study.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Hospitals Case Medical Center
Cleveland, Ohio, 44106, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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