Can new tests unlock hidden cognitive changes in down syndrome?

NCT ID NCT04208685

Completed Knowledge-focused Sponsor: Children's Hospital Medical Center, Cincinnati Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study is testing a set of cognitive assessments for children and adults with Down syndrome. The goal is to see if these tests are reliable, valid, and sensitive enough to detect changes in attention, memory, and other thinking skills. Participants aged 6 to 35 will complete the assessments at multiple visits. The findings could help design better future treatment trials for Down syndrome.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to better ways to measure thinking and behavior changes in Down syndrome, helping future treatments show their true effects.
What could go wrong: This is an early-stage study focused on measurement tools, not a treatment. The tests may not prove sensitive enough to detect changes, and results may vary across different ages and abilities.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Down syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DOWN SYNDROME

Contacts and locations

Locations

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Colorado State University

Fort Collins, Colorado, 80523, United States

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Other studies related to the condition(s) this trial covers.