DOWN SYNDROME

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Trials to join now! 17 Not yet recruiting 6 Not yet finished but already full! 11 Completed 14 Terminated 1

First human test of new drug for Alzheimer's risk in down syndrome halted early

Disease control Terminated

This early-stage study aimed to check the safety and how the body processes a new drug called ION269 in adults with Down syndrome who have brain amyloid, a protein linked to Alzheimer's disease. Only one person was enrolled before the study was stopped. The main goal was to see i…

Matched conditions: DOWN SYNDROME

Phase: PHASE1 • Sponsor: Ionis Pharmaceuticals, Inc. • Aim: Disease control

Last updated Mar 30, 2026 14:29 UTC

DOWN SYNDROME

Get alerted when new DOWN SYNDROME trials appear

First human test of new drug for Alzheimer's risk in down syndrome halted early