DEGENERATIVE DISC DISEASE
Clinical trials for DEGENERATIVE DISC DISEASE explained in plain language.
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New titanium cage tested to fix neck pain
Disease control OngoingThis study is testing a new type of titanium cage used in a common neck surgery called ACDF. The surgery aims to relieve pain and improve function in people with worn-out discs in their neck. Researchers will follow 50 patients for two years to see how well the bone heals and if …
Matched conditions: DEGENERATIVE DISC DISEASE
Phase: NA • Sponsor: Corewell Health East • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New spinal hardware put to the test in major safety trial
Disease control ENROLLING_BY_INVITATIONThis study is testing the safety and effectiveness of two specific spinal implant systems used in back surgery. It will enroll 150 adults with serious neck or upper back problems from injuries, tumors, or wear-and-tear conditions. Researchers will follow patients for two years af…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Decade-Long checkup on artificial neck discs
Disease control ENROLLING_BY_INVITATIONThis study is tracking patients for 10 years after they received an artificial disc implant in their neck to treat degenerative disc disease. It aims to see how safe and effective the implant remains over the long term, specifically for patients who had two discs replaced. The re…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Looking back at a Two-Level neck disc replacement
Disease control ENROLLING_BY_INVITATIONThis study is looking back at the safety and performance of a specific artificial disc implant (prodisc® C Vivo) when used to replace two damaged discs in the neck. It will review the medical records and X-rays of 200 patients who have already received this implant to see how wel…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: Centinel Spine • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New bone graft tested to help spinal fusion heal better
Disease control ENROLLING_BY_INVITATIONThis study is observing how well a bone graft material called Virtuos works for spinal fusion surgery in people with degenerative disc disease. Researchers will follow 150 patients who receive this graft during their standard spinal fusion surgery and check if their spine has suc…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: Orthofix Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New protein fibers aim to heal the spine
Disease control ENROLLING_BY_INVITATIONThis study is testing whether a material called Natural Matrix Protein (NMP) fibers can help bones grow together properly after spinal fusion surgery. It will involve 200 people who have already had surgery for conditions like degenerative disc disease or spinal stenosis. Researc…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: Induce Biologics USA Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New neck implants tested for safety and pain relief
Disease control ENROLLING_BY_INVITATIONThis study is testing the safety and effectiveness of two specific spinal implants for people with degenerative disc disease or instability in their neck. The research will follow 150 patients for two years after their surgery to see how well the implants work and whether they re…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New bone graft material could help spinal fusion patients heal better
Disease control OngoingThis study is testing whether a new bone graft material called P-15L works as well as standard bone graft materials for spinal fusion surgery. The trial involves 290 adults with degenerative disc disease who need spinal fusion surgery. Researchers are comparing how well the new m…
Matched conditions: DEGENERATIVE DISC DISEASE
Phase: NA • Sponsor: CeraPedics, Inc • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New drug aims to boost healing in back surgery
Disease control OngoingThis study is testing if a single dose of an experimental drug, AGA111, can help patients heal better after spinal fusion surgery for severe lower back pain. About 400 adults who have not gotten relief from other treatments will have the drug or a placebo applied during their sur…
Matched conditions: DEGENERATIVE DISC DISEASE
Phase: PHASE3 • Sponsor: Angitia Biopharmaceuticals • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New device tested to help people with severe neck pain walk away from surgery faster
Disease control OngoingThis study is testing a new medical device designed to help people with severe, multi-level neck pain from degenerative disc disease. It is for patients who need complex spine fusion surgery and haven't been helped by other treatments like physical therapy or medication. The tria…
Matched conditions: DEGENERATIVE DISC DISEASE
Phase: NA • Sponsor: Providence Medical Technology, Inc. • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Major study tests new spinal implants for chronic back pain
Disease control ENROLLING_BY_INVITATIONThis study is testing the safety and effectiveness of specific spinal implants used in back surgery. It will follow 1,050 adults with degenerative spine conditions for two years after their surgery. The main goals are to see how well the bones fuse together and to track any compl…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 24, 2026 12:03 UTC
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Titanium vs. plastic: the battle for a better backbone
Disease control OngoingThis study is testing whether a new type of textured titanium cage works better than the standard plastic cage for spinal fusion surgery. It involves 100 adults with severe back problems who haven't improved with other treatments. Researchers will follow patients for two years to…
Matched conditions: DEGENERATIVE DISC DISEASE
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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Back surgery Implant's Real-World performance under review
Disease control TerminatedThis study aimed to collect real-world, long-term data on a specific spinal implant (Arcadius XP L) used in back fusion surgery. It planned to follow 60 patients for at least one year after their surgery to see how well the implant worked and check for any safety issues. The stud…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: Aesculap AG • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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Decade-Long checkup on artificial neck discs
Disease control OngoingThis study is tracking patients for 10 years after they received an artificial disc implant called the Simplify Disc to treat neck pain and disc disease. It aims to see how well the implant holds up over the long term and how safe it remains. The study is following 131 patients w…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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Which spinal implant works best? major study compares three materials
Disease control ENROLLING_BY_INVITATIONThis study compares three different spinal implant materials used in back fusion surgery for people with degenerative disc disease or spinal slippage. Researchers will follow 300 patients for two years to see which implant material helps bones fuse together best and provides the …
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 02, 2026 15:24 UTC
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Robots vs. surgeons: european trial tests best way to place spinal screws
Diagnosis OngoingThis European study compares three different surgical techniques for placing screws in the spine during back surgery. Researchers are testing robot-guided, computer-navigated, and traditional freehand methods in 932 patients with various spinal conditions. The goal is to determin…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: Marc Schröder • Aim: Diagnosis
Last updated Apr 01, 2026 14:40 UTC
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Stem cell shot for bad backs? trial withdrawn before start
Symptom relief TerminatedThis study aimed to see if a patient's own stem cells, taken from their bone marrow and injected into a worn spinal disc, would work better than a standard steroid injection to ease chronic low back pain. It planned to enroll adults with long-term pain from one or two degenerated…
Matched conditions: DEGENERATIVE DISC DISEASE
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Doctors map the road to recovery after back surgery
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand how long it takes for hip and leg strength to return after two common types of lower back surgery (LLIF or ALIF). Researchers will measure muscle strength in 22 patients before surgery and at several points afterward using a special device. The goal …
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC