Spine implant safety under the microscope: 1,050 patients enrolled
NCT ID NCT04418830
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is tracking 1,050 adults who are getting NuVasive interbody implants during spine surgery for conditions like degenerative disc disease or spinal stenosis. Researchers are monitoring complications, bone fusion, and patient-reported pain relief over 24 months. The goal is to better understand the implants' safety and long-term performance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
NuVasive interbody implants (medical device)
What this could lead to
If successful, this study could confirm that these implants are safe and effective for treating degenerative spine conditions, helping guide future surgical decisions.
What could go wrong
This is an observational study, not a randomized trial, so results may not prove superiority over other treatments. Complications like implant failure or non-fusion are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Atlantic Brain and Spine
Wilmington, North Carolina, 28401, United States
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Beaumont Hospital Research Institute
Royal Oak, Michigan, 48073, United States
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Columbia Orthopaedics Group
Columbia, Missouri, 65201, United States
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DuPage Medical Group
Naperville, Illinois, 60540, United States
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Duke University
Durham, North Carolina, 27710, United States
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Hartford Healthcare Bone and Joint Institute
Hartford, Connecticut, 06106, United States
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Hoag Orthopedics
Orange, California, 92868, United States
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Lyerly Neurosurgery
Jacksonville, Florida, 32207, United States
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Northwestern University
Chicago, Illinois, 60610, United States
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Ohio State University
Dublin, Ohio, 43016, United States
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Summa Health
Akron, Ohio, 44320, United States
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UPMC Presbyterian
Pittsburgh, Pennsylvania, 15213, United States
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University of California San Diego
La Jolla, California, 92037, United States
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University of Virginia
Charlottesville, Virginia, 22908, United States
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Valley Spine Care
Merced, California, 95348, United States
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Verma Spine
Los Alamitos, California, 90720, United States