Which implant fuses best? new study aims to find out

NCT ID NCT03649490

ENROLLING_BY_INVITATION Disease control Sponsor: NuVasive Source: ClinicalTrials.gov ↗

First seen Jan 04, 2026 · Last updated May 12, 2026 · Updated 14 times

Summary

This study looks at three types of spinal implants used in a specific surgery (XLIF) for people with degenerative disc disease or a mild spine slip. About 300 adults will receive one of the implants along with bone graft material. The goal is to see which implant leads to the best bone fusion and pain relief over two years.

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Contacts and locations

Locations

  • Atlantic Brain and Spine

    Wilmington, North Carolina, 28401, United States

  • Columbia Orthopedic Group Research

    Columbia, Missouri, 65201, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Evergreen Health

    Kirkland, Washington, 98034, United States

  • Hartford Healthcare Bone and Joint Institute

    Hartford, Connecticut, 06106, United States

  • Lyerly Neurosurgery

    Jacksonville, Florida, 32207, United States

  • OrthoCarolina

    Charlotte, North Carolina, 28207, United States

  • Orthopaedic Institute of Western Kentucky

    Paducah, Kentucky, 42001, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Suburban Hospital, Johns Hopkins Medicine

    Bethesda, Maryland, 20814, United States

  • The Spine Clinic of OKC

    Oklahoma City, Oklahoma, 73114, United States

  • UT Health San Antonio

    San Antonio, Texas, 78229, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

  • University of South Florida Department of Neurosurgery, Tampa General Hospital

    Tampa, Florida, 33606, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22903, United States

Conditions

Explore the condition pages connected to this study.