Spine implant showdown: which material fuses best?
NCT ID NCT03649490
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 300 adults aged 18-80 who need spinal fusion surgery for degenerative disc disease or spondylolisthesis. It compares three types of interbody implants (PEEK, 3D-printed titanium, and another) used with bone graft material. Researchers will track how well the bones fuse over 24 months and whether patients report less pain and better function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
spinal implant (PEEK or 3D-printed titanium) with bone graft
What this could lead to
If successful, this study could help surgeons choose the best implant material for spinal fusion, potentially improving fusion rates and reducing pain.
What could go wrong
This is an observational study, not a randomized trial, so results may not prove one implant is better. Fusion success depends on many factors, and individual outcomes vary.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Atlantic Brain and Spine
Wilmington, North Carolina, 28401, United States
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Columbia Orthopedic Group Research
Columbia, Missouri, 65201, United States
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Duke University
Durham, North Carolina, 27710, United States
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Evergreen Health
Kirkland, Washington, 98034, United States
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Hartford Healthcare Bone and Joint Institute
Hartford, Connecticut, 06106, United States
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Lyerly Neurosurgery
Jacksonville, Florida, 32207, United States
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OrthoCarolina
Charlotte, North Carolina, 28207, United States
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Orthopaedic Institute of Western Kentucky
Paducah, Kentucky, 42001, United States
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Rush University Medical Center
Chicago, Illinois, 60612, United States
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Suburban Hospital, Johns Hopkins Medicine
Bethesda, Maryland, 20814, United States
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The Spine Clinic of OKC
Oklahoma City, Oklahoma, 73114, United States
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UT Health San Antonio
San Antonio, Texas, 78229, United States
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
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University of South Florida Department of Neurosurgery, Tampa General Hospital
Tampa, Florida, 33606, United States
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University of Virginia Health System
Charlottesville, Virginia, 22903, United States