Could a disc injection replace surgery for back pain?

NCT ID NCT06615505

Ongoing Disease control Sponsor: VIVEX Biologics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a single injection of VIA Disc NP, a processed human disc tissue, for people with long-term lower back pain from degenerated discs. About 121 participants will receive either the injection or a sham procedure. The goal is to see if the injection safely reduces pain and improves function over 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: VIA Disc NP (a processed human disc tissue allograft injected into the disc)
What this could lead to: If it works, this could offer a new, non-surgical option to reduce back pain and improve function for people with degenerated discs.
What could go wrong: This is an early phase 2 trial with only 121 participants, so results may not apply to everyone. The sham procedure may also produce some benefit, making it hard to prove the treatment works.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEGENERATIVE DISC DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEGENERATIVE DISC DISEASE DISC DEGENERATION LUMBAR DISCOGENIC PAIN

Contacts and locations

Locations

Australian Medical Research

Hurstville, New South Wales, 2220, Australia
Cercare Clinical Research

Wayville, South Australia, 5034, Australia
Genesis Research Services Pty Ltd

Broadmeadow, New South Wales, 2292, Australia
Monash House Research Centre Pty Ltd

Clayton, Victoria, 3168, Australia
Sydney Pain Research Centre

Wahroonga, New South Wales, 2076, Australia

More trials for these conditions

Other studies related to the condition(s) this trial covers.