One-Shot stem cell treatment aims to quiet aching backs

NCT ID NCT06325566

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a single injection of rexlemestrocel-L (a type of stem cell) combined with hyaluronic acid can reduce chronic low back pain for at least 12 months. It involves 300 adults with moderate to severe pain from a worn spinal disc who haven't improved with standard care. The main goal is to measure pain relief and safety compared to a control injection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEGENERATIVE DISC DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AdventHealth Hendersonville

    Hendersonville, North Carolina, 28792, United States

  • Apex Research Group

    Fair Oaks, California, 95628, United States

  • Axsendo Clinical Research/Summa Pain Care

    Phoenix, Arizona, 85085, United States

  • Axsendo Clinical Research/Texas Institute of Pain and Spine

    Pearland, Texas, 77584, United States

  • Bold City Clinical Research

    Jacksonville, Florida, 32224, United States

  • Boomerang Health Care

    Concord, California, 94520, United States

  • Cantor Spine Center at the Paley Orthopedic & Spine Institute

    Fort Lauderdale, Florida, 33306, United States

  • Clinical Investigations, LLC

    Edmond, Oklahoma, 73034, United States

  • Clinical Trials of South Carolina

    Charleston, South Carolina, 29406, United States

  • Colorado Spine Partners/The Denver Spine and Pain Institute

    Greenwood, Colorado, 80111, United States

  • Conquest Research LLC

    Winter Park, Florida, 32789, United States

  • Elevate Clinical Research

    Rockville, Maryland, 20852, United States

  • Emory Healthcare

    Dunwoody, Georgia, 30338, United States

  • Eximia EquiHealth Research LLC/Emerge Ortho

    Durham, North Carolina, 27704, United States

  • Hawaii Pain & Spine

    Kailua, Hawaii, 96734, United States

  • Innovative Pain Treatment Solutions

    San Diego, California, 92111, United States

  • Institute of Precision Pain Medicine

    Corpus Christi, Texas, 78414, United States

  • Interventional Pain Institute

    The Villages, Florida, 32162, United States

  • Iqra Research

    Edgewood, Kentucky, 41017, United States

  • Memorial Orthopaedic Surgical Group

    Long Beach, California, 90806, United States

  • Meta Medical Research Institute, LLC

    Dayton, Ohio, 45432, United States

  • New Life Medical Research Center

    Hialeah, Florida, 33012, United States

  • Newport Therapeutics

    Newport Beach, California, 92660, United States

  • OSS Health

    York, Pennsylvania, 17402, United States

  • Oasis Clinical Research

    Las Vegas, Nevada, 89121, United States

  • Pain Institute of Southern Arizona

    Tucson, Arizona, 85710, United States

  • Paradigm Health System

    Slidell, Louisiana, 70458, United States

  • Paradigm Research Center/Houston Scoliosis and Spine Institute

    Houston, Texas, 77030, United States

  • Reno Tahoe Pain Associates

    Reno, Nevada, 89511, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Source Healthcare

    Santa Monica, California, 90403, United States

  • The Kahan Center

    Annapolis, Maryland, 21401, United States

  • TriWest Research Associates

    Chula Vista, California, 91910, United States

  • University of California-Davis Spine Center

    Sacramento, California, 95816, United States

  • University of California-San Francisco

    San Francisco, California, 94143, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Rochester

    Rochester, New York, 14611, United States

  • VA iSpine Physicians

    Richmond, Virginia, 23238, United States

  • Vista Clinical Research

    Newnan, Georgia, 30265, United States

  • West Virginia University

    Martinsburg, West Virginia, 25401, United States