CHILDHOOD CANCER

This study tests new cancer drugs that are chosen based on the unique genetic makeup of each child's tumor. It is for children, teens, and young adults with advanced solid tumors, brain tumors, or lymphomas that have not responded to standard treatments. The goal is to find the r…

This study tests a program called CHEF that helps childhood cancer survivors and their families cook and eat healthier foods. The goal is to improve heart health after cancer treatment. About 17 children who finished chemotherapy or radiation will take part. Researchers will meas…

This study looks at whether a wearable device and a symptom questionnaire can accurately detect autonomic dysfunction (a nerve problem affecting heart rate and other automatic body functions) in survivors of childhood leukemia and lymphoma. About 188 adult survivors will use a bi…

This study tests a computer program called C-SCAT that helps adolescents and young adults with cancer track and manage their symptoms. About 126 participants will either use the tool or receive usual care. The goal is to see if the tool boosts their confidence and ability to hand…

This study follows 3,000 childhood cancer survivors in Switzerland to understand long-term health problems caused by past cancer treatments. Participants undergo regular check-ups, lab tests, and questionnaires as part of their normal follow-up care. The goal is to better detect …

This study aims to find blood markers that show if a child's brain has been injured by cancer treatment. Researchers will collect blood samples from 560 children with brain tumors before and after surgery, radiation, or chemotherapy, and compare them to samples from healthy child…

This study collects health information from up to 30,000 children and adults who have or had childhood cancer at St. Jude Children's Research Hospital. The goal is to track long-term outcomes and late side effects of treatment. No new treatments are tested; instead, researchers u…

This study tests a new tool called HPARSS to help doctors identify childhood cancer survivors who may have vision or hearing problems from their past treatment. Researchers will see if the tool makes it easier for doctors to order the right screening tests. The goal is to catch t…

This study is testing an online program called PLAY for caregivers of young children who have finished cancer treatment or are on maintenance therapy. The program includes online lessons and video coaching sessions to help caregivers support their child's school readiness and man…

This study collects and freezes testicular tissue from prepubertal boys who are about to receive cancer treatment that is very likely to cause infertility. The tissue is stored for possible future use to restore fertility, and a portion is used for research to understand how sper…

This study looks at why some survivors of childhood acute lymphoblastic leukemia (ALL) have weak muscles. Researchers will use MRI scans, ultrasound, and small muscle biopsies to measure how well muscle cells produce energy. The goal is to learn more about the link between cancer…