CHILDHOOD CANCER

This study tests a program called CHEF that helps childhood cancer survivors and their families cook and eat healthy foods. The goal is to support heart health after cancer treatment. About 17 children who finished chemotherapy or radiation will take part. Researchers will measur…

This trial tests whether giving children and teens with advanced solid tumors, brain tumors, or lymphomas drugs that match their tumor's genetic profile can help. About 90 participants will receive one of four drug combinations based on their tumor's molecular features. The goal …

This study looks at whether a wearable heart monitor and a symptom questionnaire can accurately detect autonomic dysfunction—a condition affecting heart rate and blood pressure control—in survivors of childhood leukemia and lymphoma. Researchers will compare these remote methods …

This Canadian study is testing whether cannabinoid oils (CBD and THC) can safely help manage symptoms like pain in children aged 4-17 with relapsed or refractory cancer. The trial will enroll 60 kids across three hospitals, giving them different ratios of CBD to THC oils to see w…

This study tests whether a six-week at-home light therapy program is practical and helpful for childhood cancer survivors who have nerve pain or numbness from chemotherapy. Twenty survivors aged 5 and older will use a light therapy device on their symptoms for 15 minutes, three d…

This study tests a computer program called C-SCAT that helps adolescents and young adults with cancer track and manage their symptoms. Participants use the tool to rate symptoms, find patterns, and plan how to cope. The goal is to see if using C-SCAT boosts their confidence and a…

This study tests if creating a short digital story about their cancer journey can reduce depressive symptoms and improve self-esteem and quality of life in Hong Kong Chinese teens who have finished cancer treatment. About 248 survivors aged 13-18 will either join four 2.5-hour wo…

This study tests an online program called PLAY for caregivers of young children who have finished cancer treatment. The program includes 7 modules and coaching sessions to help with parenting, stress, and school readiness. Researchers want to see if caregivers find it easy to use…

Many parents of childhood cancer survivors struggle with intense fear that their child's cancer will come back. This study tests a 7-session group therapy program, adapted from one used for adult survivors, to see if it is acceptable and helpful for parents. Thirty-six parents in…

This study follows people who survived childhood cancer for at least five years to learn about the long-term effects of the disease and its treatment. Researchers send questionnaires to survivors to gather information on quality of life, physical and mental health, medication use…

Childhood cancer survivors who received certain treatments are at higher risk for heart problems. This study tests whether an online program with personalized education and motivational coaching can encourage them to get a recommended heart screening. About 350 adult survivors wi…

This study collects health information from up to 30,000 children and adults who have or had childhood cancer at St. Jude Children's Research Hospital. The goal is to track their long-term outcomes and any late side effects from treatment. No new treatments are tested—this is pur…

This study is testing a new tool called HPARSS that helps doctors identify childhood cancer survivors at risk for hearing or vision problems. The tool uses a patient's past cancer treatments to flag who needs screening. Researchers will see if this approach leads to more kids get…

This study tests whether short educational videos can help young adults who survived childhood cancer learn about and get the HPV vaccine. The researchers will enroll 55 survivors aged 18-26 who haven't finished the vaccine series. Participants will watch the videos on Facebook a…

This study looks at 500 adult survivors of childhood cancer to see if a newer type of heart ultrasound, called speckle tracking, can find heart problems earlier than the usual method. Researchers want to know if this technique can detect heart damage sooner, which could help with…

This study aims to help boys who need strong cancer treatments that could harm their ability to have children later. For those who haven't gone through puberty, doctors will freeze a small piece of testicular tissue to save stem cells. The goal is to protect future fertility and …

This study uses non-invasive MRI and MRS scans to measure how well muscle cells produce energy in adults who survived childhood acute lymphoblastic leukemia (ALL). Researchers will compare 60 survivors with low muscle mass to healthy volunteers. The goal is to understand why many…

This study follows 140 children who have had cancer treatment to check how their lungs are working over time. Researchers use breathing tests, lung scans, and breath samples to spot early signs of lung problems. The goal is to better understand and detect lung damage caused by ca…

This study tests whether simple digital tools—like letters and text messages—can encourage adolescent and young adult survivors of childhood cancer to schedule and attend long-term follow-up appointments. About 530 participants who are overdue for care will receive different comb…

This observational study aims to find blood markers that show brain injury caused by cancer treatments in children with brain tumors. Researchers will collect plasma samples from 560 children before and after surgery, during radiation or chemotherapy, and up to three years later.…

This study collects and freezes testicular tissue from prepubertal boys before they start cancer treatment that has a high risk of causing infertility. The tissue is stored for potential future use to restore fertility and for research to better understand germ cell development. …

This study looks at how two common chemotherapy drugs, vincristine and doxorubicin, affect bladder function and urine composition in children who have finished cancer treatment. Researchers will use simple, non-invasive tests to measure urine flow and check for bladder-related pr…

This study follows 3,000 childhood cancer survivors in Switzerland to learn about long-term health problems caused by cancer treatments. Participants undergo physical exams, lab tests, and questionnaires during regular follow-up visits. The goal is to better understand and manage…