New imaging study seeks to unlock muscle fatigue in cancer survivors

NCT ID NCT06819475

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study uses non-invasive MRI and MRS scans to measure how well muscle cells produce energy in adults who survived childhood acute lymphoblastic leukemia (ALL). Researchers will compare 60 survivors with low muscle mass to healthy volunteers. The goal is to understand why many survivors experience muscle weakness, which could lead to better support strategies in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could reveal why childhood leukemia survivors often have muscle weakness, pointing toward future therapies.
What could go wrong
This is an early observational study with only 60 participants, so results may not apply to all survivors. It does not test any treatment.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia childhood malignant neoplasm Muscle Weakness neoplasm Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Email: •••••@•••••

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