Can a simple blood test predict brain damage from childhood cancer treatment?

NCT ID NCT07381959

Recruiting now Knowledge-focused Sponsor: Uppsala University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study aims to find blood markers that show brain injury caused by cancer treatments in children with brain tumors. Researchers will collect plasma samples from 560 children before and after surgery, during radiation or chemotherapy, and up to three years later. They will compare results with healthy children to identify treatment-specific biomarkers that could guide safer therapies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could identify blood tests that detect brain injury early, helping doctors tailor treatments to reduce long-term harm in children.
What could go wrong: This is an early observational study, not a treatment trial. It may not find clear biomarkers, and results may not apply to all children or hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain cancer brain neoplasm childhood malignant neoplasm neoplasm primary brain neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN TUMOR CHILDHOOD BRAIN TUMOR CHILDHOOD CANCER

Contacts and locations

Locations

Uppsala University
RECRUITING

Uppsala, Sweden

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