Rebooting immunity: can vaccines shield childhood cancer survivors from preventable diseases?
NCT ID NCT00505063
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This trial investigates how well routine childhood vaccines work in children who have recently finished chemotherapy for cancer. The goal is to see if revaccination can restore protective immunity against diseases like measles, mumps, and whooping cough. Participants receive a series of standard vaccines over several months, and their antibody levels are measured to gauge protection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a series of routine childhood vaccines (Prevnar 13, Menactra II, MMR, varicella, HPV, Hib, Pediarix, hepatitis B)
- What this could lead to
- If successful, this could establish a standard revaccination schedule to protect childhood cancer survivors from preventable diseases like measles, mumps, and whooping cough.
- What could go wrong
- This is a relatively small, single-center trial, and immune responses may vary widely in children whose immune systems are still recovering from chemotherapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan-Kettering Cancer Center
New York, New York, 10021, United States
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