Chemo's hidden toll on Kids' bladders revealed

NCT ID NCT04993859

Recruiting now Knowledge-focused Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how two common chemotherapy drugs, vincristine and doxorubicin, affect bladder function and urine composition in children who have finished cancer treatment. Researchers will use simple, non-invasive tests to measure urine flow and check for bladder-related proteins. The goal is to better understand and detect bladder problems early in childhood cancer survivors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better understand and monitor bladder problems in childhood cancer survivors.
What could go wrong: This is an observational study, not a treatment trial. It may not lead to direct changes in care, and results may not apply to all children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

childhood malignant neoplasm urinary bladder disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLADDER DYSFUNCTION SURVIVORS OF CHILDHOOD CANCER

Contacts and locations

Locations

Children's Hospital Colorado
RECRUITING

Aurora, Colorado, 80045, United States

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