BREAST CANCER METASTATIC

This study is testing a new drug called evorpacept, given alongside standard cancer treatments, for people with advanced breast cancer that has spread and stopped responding to prior therapy. It aims to see if this combination can better control the cancer and is safe for patient…

This early-stage trial is testing whether adding an experimental drug called avasopasem to standard breast cancer therapy is safe and might help when the initial treatment stops working. The study will enroll about 35 women with metastatic, hormone receptor-positive breast cancer…

This study aims to see how well a drug called sacituzumab govitecan works for patients with advanced HER2-negative breast cancer in real-world medical settings across China. It will follow about 200 patients who have already received this treatment to measure how long the cancer …

This early-stage study aims to find the safest and most effective dose of the drug abemaciclib when given at the same time as targeted radiation therapy. It is for people with advanced, hormone-sensitive breast cancer that has spread to the bones. The goal is to see if this combi…

This study is testing a new antibody drug called OM-RCA-01 in people with advanced cancers that have spread and have a specific protein (FGFR1). The main goals are to find a safe dose and see if the drug can slow down tumor growth. About 58 people with certain types of metastatic…

This early-stage trial is testing a new treatment for people with metastatic pancreatic or breast cancer. The goal is to see if a combination of high-dose chemotherapy drugs, vitamins, and the patient's own stem cells is safe and can overcome the cancer's resistance to treatment.…

This study is testing whether a new immunotherapy combination can help people with advanced metastatic breast cancer live longer when standard treatments have stopped working. The trial will compare the experimental treatment against whatever therapy a doctor would normally choos…

This early-stage study is testing a new drug called Sapu003 in people with advanced cancers that have spread or cannot be removed by surgery. The main goal is to find the safest and most effective dose, and to see how the body processes the drug. The study includes 27 adults with…

This early-stage study is testing a new oral medication called INX-315 in people with advanced cancers that have spread or stopped responding to standard treatments. It aims to find a safe dose and see if the drug can help control cancers like certain types of breast and ovarian …

This is the first human study of an experimental drug called SLV-154 for people with advanced solid tumors that have spread. The main goal is to find the highest safe dose and understand how the body processes the drug. About 70 adults with one of ten specific advanced cancers wh…

This study is testing a drug called trastuzumab deruxtecan (T-DXd) in adults whose advanced breast cancer has spread and has tested completely negative for a protein called HER2. The goal is to see if this drug, which combines a targeted antibody with a chemotherapy agent, can sh…

This is an early study to test the safety of a new two-part treatment for people with advanced breast cancer that has spread or cannot be removed by surgery. The treatment involves giving patients their own modified immune cells (CLBR001), followed by a biologic drug (ABBV-461) t…

This study is testing two new imaging agents for PET/CT scans to see if they can better detect and characterize breast cancer tumors. The goal is to see if these new scans can more accurately show where cancer is located and how much of certain proteins the tumors have. This coul…

This study aims to improve the diagnosis of metastatic breast cancer by comparing different methods of testing for a specific gene mutation called PIK3CA. Researchers will test 100 patients using both a standard tissue biopsy and a less invasive blood test (liquid biopsy) to see …

This study is testing a new imaging technique to help surgeons see if breast cancer has spread to nearby lymph nodes during surgery. Doctors apply a special fluorescent dye to the removed lymph node tissue and use a special camera to see if cancer cells are present. The goal is t…

This online study aims to understand the perspectives of women who have completed treatment for early-stage breast cancer. Researchers want to know if these women are willing and able to make healthier food choices, particularly by reducing processed foods. Participants will comp…