New drug SLV-154 enters human testing for Hard-to-Treat cancers

NCT ID NCT06771219

Recruiting now Disease control Sponsor: Solve Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This early-phase study tests a new drug called SLV-154 in about 70 people with advanced solid tumors (like head and neck, lung, breast, or ovarian cancer) that have spread. The main goal is to find a safe dose and check for side effects. Researchers will also watch for any signs that the drug is working against the cancer.

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Conditions

The condition(s) this trial relates to.

breast cancer cancer cervical cancer cervical carcinoma endometrial cancer endometrium neoplasm head and neck squamous cell carcinoma metastatic malignant neoplasm neoplasm Neoplasm Metastasis non-small cell lung carcinoma ovarian cancer sarcoma small cell lung carcinoma thyroid cancer urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED CANCER ADVANCED SOLID TUMOR BREAST CANCER, METASTATIC CERVICAL CANCER METASTATIC ENDOMETRIAL CANCER METASTATIC CANCER NSCLC OVARIAN CANCER SARCOMA SCLC SQUAMOUS CELL CANCER OF HEAD AND NECK (SCCHN) THYROID CANCER UROTHELIAL CANCER

Contacts and locations

Locations

Astera Cancer Care
RECRUITING

East Brunswick, New Jersey, 08816, United States
Hoag Memorial Hospital Presbyterian
RECRUITING

Newport Beach, California, 92663, United States
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Mays Cancer Center; University of Texas Health San Antonio
RECRUITING

San Antonio, Texas, 78229, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Northwest Medical Specialties, PLLC
RECRUITING

Tacoma, Washington, 98405, United States
Oncology Consultants
RECRUITING

Houston, Texas, 77030, United States
University Hospitals Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University of Washington / Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States
Washington University
RECRUITING

St Louis, Missouri, 63110, United States

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