Could a new scan unlock better breast cancer treatment?

NCT ID NCT06732336

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a special PET scan using a radioactive tracer called 89Zr-trastuzumab to find low levels of HER2 in metastatic breast cancer. Researchers aim to see if this scan can better detect tumors that might respond to newer drugs like Enhertu. The trial will involve 40 adults with HER2-low breast cancer, and results could help personalize treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

89Zr-trastuzumab (a radioactive tracer for PET imaging)

What this could lead to

If successful, this imaging method could help doctors see which tumors have low HER2, guiding personalized treatments like Enhertu for more patients.

What could go wrong

This is an early-phase trial with only 40 participants, so results may not apply broadly. The imaging may not reliably detect all low-HER2 tumors, and there are no direct treatment benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre de recherche du CHUS

    RECRUITING

    Sherbrooke, Quebec, J1H5N4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact