New blood test could personalize breast cancer care

NCT ID NCT06762483

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to create a blood test (liquid biopsy) that can detect two key genetic mutations, ESR1 and gBRCA, in patients with a common type of metastatic breast cancer (HR+/HER2-). The test would help doctors choose the most effective treatments without needing a tissue biopsy. Researchers will also build a digital gene library to support this diagnostic approach. The study involves 80 participants and is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

liquid biopsy (blood test)

What this could lead to

If successful, this could lead to a simple blood test that helps doctors choose the right treatments for people with metastatic breast cancer, potentially improving outcomes.

What could go wrong

This is an early-stage diagnostic study with only 80 participants, so the test may not prove accurate enough for widespread use. It does not test a new treatment, so direct patient benefit is not guaranteed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hormone receptor-positive breast cancer Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • European Institute of oncology

    RECRUITING

    Milan, Italy, 20141, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••