AUTOIMMUNE DISEASES

This study tested how well flu vaccines work in people with autoimmune diseases like lupus or rheumatoid arthritis, many of whom take medications that weaken their immune systems. Researchers gave 234 participants both seasonal and H1N1 flu vaccines and measured their immune resp…

This study documented how well the GLOBAFFIN® device works in real-world medical settings for people with autoimmune diseases. The device filters harmful antibodies from patients' blood to help control their conditions. Researchers tracked 34 adult patients who were already sched…

This study tested whether adding a drug called eculizumab to standard treatment could improve outcomes for people with anti-GBM disease, a severe autoimmune condition that rapidly attacks the kidneys. Sixteen adult patients with confirmed disease received the drug, which blocks a…

This pilot study tested a combined transplant from a partially matched family donor. It aimed to treat patients who had both a serious blood disorder (like leukemia) and advanced kidney disease at the same time. The goal was to cure the blood disorder and restore kidney function …

This study tested whether a coaching program is practical and acceptable for young adults with childhood-onset arthritis (like juvenile idiopathic arthritis or lupus) as they move from pediatric to adult rheumatology care. The program aimed to provide support and teach self-manag…

This study followed 80 patients with pemphigus, a serious autoimmune skin disease, who received rituximab treatment years earlier. Researchers tracked how many patients remained disease-free long-term and monitored for any delayed side effects. The goal was to understand the last…

This large study investigated whether taking daily vitamin D or fish oil supplements could help prevent new autoimmune diseases, reduce body-wide inflammation, or lessen chronic knee pain. It involved over 25,000 U.S. adults without a prior history of cancer or heart disease. Res…

This early-stage study tested the safety and how the body processes multiple doses of a new drug called RLYB116. It involved 16 healthy adults to see how well they tolerated the drug and to measure its levels and effects in the blood. The goal was to gather initial safety data be…

This was a small, completed lab study that tested whether specially engineered versions of a natural immune protein (called IL-2 muteins) could selectively boost a type of calming immune cell (regulatory T cells) taken from patients with various autoimmune and inflammatory diseas…