AUTOIMMUNE DISEASES
Clinical trials for AUTOIMMUNE DISEASES explained in plain language.
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Can the flu shot protect patients with autoimmune conditions?
⭐️ VACCINE ⭐️ CompletedThis study looked at how well the seasonal and H1N1 flu vaccine works and how safe it is for people with autoimmune diseases like lupus or vasculitis. Researchers measured antibody levels three weeks after each shot. The goal was to see if the vaccine provides protection even in …
Matched conditions: AUTOIMMUNE DISEASES
Phase: PHASE4 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: ⭐️ VACCINE ⭐️
Last updated Apr 29, 2026 15:05 UTC
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New autoimmune drug VIS171 passes first safety check in humans
Disease control CompletedThis early-stage study tested a new drug called VIS171 in 61 people, first in healthy volunteers and then in patients with autoimmune diseases. The main goal was to check safety and how the body processes the drug. Results will help decide if further testing is warranted.
Matched conditions: AUTOIMMUNE DISEASES
Phase: PHASE1 • Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Disease control
Last updated May 17, 2026 00:28 UTC
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Blood filter shows promise for autoimmune patients
Disease control CompletedThis study tested the safety and effectiveness of a medical device called GLOBAFFIN® in 34 adults with autoimmune diseases. The device filters harmful antibodies from the blood to help control the disease. The main goal was to measure how much antibody levels dropped after each t…
Matched conditions: AUTOIMMUNE DISEASES
Phase: NA • Sponsor: Fresenius Medical Care Deutschland GmbH • Aim: Disease control
Last updated May 17, 2026 00:25 UTC
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Vitamin d and fish oil: a simple fix for autoimmune and knee pain?
Disease control CompletedThis study looked at whether taking daily vitamin D or fish oil supplements could lower the risk of autoimmune diseases (like rheumatoid arthritis), reduce signs of inflammation in the blood, and ease chronic knee pain. Over 25,000 adults without prior cancer or heart disease too…
Matched conditions: AUTOIMMUNE DISEASES
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New drug shows promise in battle against rare kidney disease
Disease control CompletedThis study tested a new antibody drug (C5 monoclonal antibody) in 16 people with anti-GBM disease, a severe autoimmune condition that attacks the kidneys. The goal was to see if the drug could prevent kidney failure better than current treatments. The approach targets part of the…
Matched conditions: AUTOIMMUNE DISEASES
Phase: PHASE2 • Sponsor: Peking University First Hospital • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Double transplant from same donor could reduce lifelong Anti-Rejection drugs
Disease control CompletedThis study tested a combined bone marrow and kidney transplant from a partially matched related donor for 10 people with both a blood disorder and chronic kidney disease. The goal was to treat both conditions and possibly reduce the need for lifelong anti-rejection drugs after th…
Matched conditions: AUTOIMMUNE DISEASES
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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Shocking relief: electrical acupoint therapy eases menstrual pain in autoimmune patients
Symptom relief CompletedThis study tested a non-invasive treatment called transcutaneous electrical acupoint stimulation (TEAS) for period pain in 52 women with rheumatoid arthritis or lupus. Participants received either TEAS or a placebo, and researchers measured pain, walking speed, and inflammation m…
Matched conditions: AUTOIMMUNE DISEASES
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated May 11, 2026 20:52 UTC
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Rituximab's Long-Term effects on pemphigus under the microscope
Knowledge-focused CompletedThis study followed 80 people with pemphigus, a severe autoimmune blistering skin disease, who had previously taken part in a trial of the drug rituximab. Researchers wanted to see how safe the drug is over many years, how often the disease returns, and how the immune system chan…
Matched conditions: AUTOIMMUNE DISEASES
Phase: PHASE3 • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated May 17, 2026 00:32 UTC
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Can immunoglobulin therapy cut infection risk in rituximab patients?
Knowledge-focused CompletedThis study followed 73 people with autoimmune diseases like rheumatoid arthritis or multiple sclerosis who were starting treatment with rituximab, a drug that suppresses the immune system. The goal was to track how many developed serious infections and identify who was most at ri…
Matched conditions: AUTOIMMUNE DISEASES
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 17, 2026 00:30 UTC
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Can coaching ease the tough transition to adult rheumatology care?
Knowledge-focused CompletedThis study tested whether coaching sessions are a practical way to help young people with rheumatic diseases (like juvenile arthritis) move from pediatric to adult rheumatology care. Researchers enrolled 26 patients and measured how many agreed to join, attended sessions, and com…
Matched conditions: AUTOIMMUNE DISEASES
Phase: NA • Sponsor: McMaster University • Aim: Knowledge-focused
Last updated May 17, 2026 00:29 UTC
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Can cutting salt and sugar tame steroid side effects?
Knowledge-focused CompletedThis study looked at whether a diet low in salt and sugar can reduce common side effects of corticosteroid treatment, like weight gain, high blood pressure, and diabetes. Fifty adults with autoimmune diseases or asthma who were starting high-dose steroids participated. Researcher…
Matched conditions: AUTOIMMUNE DISEASES
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Healthy volunteers test new Drug's safety in Early-Stage trial
Knowledge-focused CompletedThis early-stage study tested the safety and how the body handles a new drug called RLYB116 in 16 healthy adults aged 18 to 55. Participants received multiple doses, and researchers monitored side effects, drug levels, and immune reactions. The goal was to gather safety informati…
Matched conditions: AUTOIMMUNE DISEASES
Phase: PHASE1 • Sponsor: Rallybio • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
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Scientists engineer 'smarter' IL-2 to tame overactive immune systems
Knowledge-focused CompletedThis study tested specially engineered versions of a natural immune protein (IL-2) in blood samples from 67 people with autoimmune or inflammatory diseases like lupus, multiple sclerosis, and rheumatoid arthritis. The goal was to see if these modified proteins could selectively a…
Matched conditions: AUTOIMMUNE DISEASES
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Apr 24, 2026 16:18 UTC