AUTOIMMUNE DISEASES

This early-stage study is testing the safety and initial effects of a new cell therapy called RD06-04 for people with active, severe autoimmune diseases. The therapy involves modifying a patient's own immune cells (CAR-T cells) to target and remove certain harmful immune cells. T…

This is an early-stage study testing a new type of cell therapy called Prula-cel for adults with severe autoimmune diseases that haven't responded well to standard treatments. The therapy involves giving patients specially engineered immune cells designed to target and remove har…

This was an early-stage study to test the safety and find the right dose of a new oral drug called HMPL-523 for adults with immune thrombocytopenia (ITP), a condition where the immune system attacks platelets, causing a risk of bleeding. The study was designed to enroll adults wh…

This study is testing whether gentle, low-frequency electromagnetic waves can help stabilize the immune system and reduce painful flare-ups in people with autoimmune diseases like lupus, rheumatoid arthritis, and multiple sclerosis. About 120 participants will receive either real…

This study aimed to test whether a combination of four drugs could help people recently diagnosed with type 1 diabetes keep making their own insulin. The goal was to see if this treatment could protect the body's remaining insulin-producing cells better than a placebo. The trial …

This study aims to build a database to help researchers understand the autoimmune-like side effects that can occur from powerful cancer immunotherapy drugs. It will collect health data and samples from 32 adult cancer patients receiving these treatments. The goal is to learn who …

This study tests if educational visits to doctors change how often they prescribe lower-cost 'biosimilar' versions of a common drug (adalimumab/Humira) for autoimmune diseases. Researchers will compare doctors who receive the educational visit to those who do not, measuring chang…

This research study aims to understand how autoimmune diseases like lupus develop by comparing immune cells from people with autoimmune conditions, people with infectious diseases, and healthy individuals. Researchers will collect blood and sometimes bone marrow samples from 2,50…

This study aims to understand how often and why patients experience memory and thinking problems after hip or knee replacement surgery. Researchers are following 505 patients aged 50+ to track their cognitive function before and after surgery for several months. The goal is to id…