AUTOIMMUNE DISEASES

This early-stage trial is testing a therapy called CD19 CAR-T cells for people with severe autoimmune diseases that haven't improved with standard treatments. It aims to see if this approach, which involves modifying a patient's own immune cells to target and remove harmful B cel…

This is an early study to find a safe and effective dose of an experimental drug called STR-P004 for people with autoimmune kidney diseases. It will involve about 9 participants who will receive the drug through IV infusions over 1-2 months. The main goals are to check for side e…

This study is testing a drug called inectolizumab for people newly diagnosed with a rare autoimmune disease that attacks the nerves and spinal cord (NMOSD). The main goal is to see if the drug can help control the disease while allowing patients to take fewer steroids, which have…

This early-stage study is testing a new drug called S-4321 in adults with autoimmune diseases like rheumatoid arthritis, psoriasis, lupus, or eczema. The main goal is to check the drug's safety, how the body processes it, and look for early signs it might help control these condi…

This early study is testing a new type of drug that uses mRNA technology (like some COVID-19 vaccines) to treat autoimmune diseases that have come back or not responded to other treatments. It aims to find a safe dose by giving the drug to about 27 adults with conditions like lup…

This early study is testing a new injection called WGb-0301 for people with autoimmune diseases like lupus or autoimmune hepatitis that have come back or haven't responded to standard treatments. The drug uses mRNA technology to target a specific part of the immune system (B cell…

This early-stage study is testing a new mRNA therapy designed to treat several autoimmune diseases that haven't responded well to other treatments. The therapy uses technology similar to some COVID-19 vaccines to deliver instructions that target a specific part of the immune syst…

This study aims to create and test a practical system for hospitals to offer and give recommended vaccines to adults with chronic diseases or weakened immune systems. It will involve 1,500 patients, offering vaccines during their hospital visits or stays. The goal is to see if th…

This study aims to understand how disorders in blood cell production are connected to various inflammatory and autoimmune diseases. Researchers will observe 5,000 adult patients who have these conditions, collecting their health information over time. The goal is to create a deta…