New mRNA shot aims to calm stubborn autoimmune diseases

NCT ID NCT07349823

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a new drug called WGb-0301 for people with autoimmune diseases (like lupus or autoimmune hepatitis) that haven't responded to standard treatments. The drug uses mRNA technology to target and clear certain immune cells (B cells) that are causing the disease. The main goals are to find a safe dose and see if it can control the disease long-term.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autoimmune disease autoimmune hepatitis idiopathic inflammatory myopathy scleroderma systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.