MRNA technology takes on autoimmune diseases in new trial

NCT ID NCT07362758

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests a new mRNA therapy that targets CD19, a protein on immune cells, to treat autoimmune diseases like lupus and immune anemia. The treatment uses lipid nanoparticles to deliver mRNA that helps the body clear harmful B cells. About 47 participants aged 14-70 with difficult-to-treat autoimmune conditions will be enrolled to find the safest dose and see if it controls the disease.

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Conditions

The condition(s) this trial relates to.

autoimmune disease autoimmune hemolytic anemia systemic lupus erythematosus systemic sclerosis thrombocytopenia due to immune destruction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.