AUTOIMMUNE DISEASES
Clinical trials for AUTOIMMUNE DISEASES explained in plain language.
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New drug tested for severe arthritis halted early
Disease control TerminatedThis study tested an experimental drug called peresolimab in adults with moderate-to-severe rheumatoid arthritis whose current treatments weren't working well enough. About 491 participants received either the drug or a placebo to see if it safely reduced arthritis symptoms and i…
Matched conditions: AUTOIMMUNE DISEASES
Phase: PHASE2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Sleep hormone tested to halt debilitating MS progression
Disease control TerminatedThis study aimed to see if adding the hormone melatonin to the standard drug ocrelizumab could safely help slow down disability in people with a fast-progressing form of multiple sclerosis (MS). It involved 25 adults with primary progressive MS who were already stable on ocrelizu…
Matched conditions: AUTOIMMUNE DISEASES
Phase: PHASE1, PHASE2 • Sponsor: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Could a common pain reliever calm a Child's sudden OCD?
Symptom relief TerminatedThis study tested whether naproxen sodium (the medicine in Aleve) could reduce obsessive-compulsive symptoms in children with PANDAS, a condition where strep infections trigger sudden neuropsychiatric problems. It was a small, controlled trial comparing the drug to a placebo pill…
Matched conditions: AUTOIMMUNE DISEASES
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Do COVID vaccines work for people on Immune-Weakening drugs?
Knowledge-focused TerminatedThis study aimed to understand how well COVID-19 vaccines protect people with autoimmune or inflammatory diseases who take medications that weaken their immune system. Researchers compared the immune responses of 78 vaccinated patients on these drugs to those of healthy people. T…
Matched conditions: AUTOIMMUNE DISEASES
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC