Anti-Inflammatory drug studied for PANDAS-Related OCD in kids
NCT ID NCT04015596
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested the anti-inflammatory drug naproxen sodium for treating obsessive-compulsive symptoms in children aged 6-15 with PANDAS, a condition linked to strep infections. The trial was double-blind and placebo-controlled, but it was terminated early after enrolling only 2 participants. No results are available to determine if naproxen helps.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- naproxen sodium (an anti-inflammatory drug)
- What this could lead to
- If it had worked, this could have pointed toward an anti-inflammatory treatment for OCD symptoms in children with PANDAS.
- What could go wrong
- The trial was terminated early with only 2 participants, so no conclusions can be drawn. It is unclear if naproxen is effective or safe for this condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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