Sleep hormone fails to halt MS progression in early trial

NCT ID NCT03540485

First seen Feb 22, 2026 · Last updated May 05, 2026 · Updated 7 times

Summary

This study tested whether adding melatonin to a standard MS drug (ocrelizumab) could slow disability in people with progressive multiple sclerosis. The trial was stopped early after enrolling only 25 participants. It aimed to measure changes in walking, arm function, and thinking, but no clear benefit was found.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AUTOIMMUNE DISEASES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Hospital Vithas Nisa Sevilla

    Seville, Seville, 41950, Spain

  • Virgen Macarena Hospital

    Seville, Seville, 41009, Spain

  • Virgen del Rocio University Hospital

    Seville, Seville, 41013, Spain

Conditions

Explore the condition pages connected to this study.