Could ifetroban ease scleroderma lung damage?

NCT ID NCT02682511

First seen Apr 22, 2026 · Last updated May 05, 2026 · Updated 3 times

Summary

This study tests an experimental drug called ifetroban in people with a severe form of scleroderma (diffuse cutaneous systemic sclerosis) or scleroderma-related high blood pressure in the lungs. The goal is to see if the drug is safe and can improve lung function. About 34 adults will receive either ifetroban or a placebo, and researchers will monitor side effects and breathing tests over time.

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Contacts and locations

Locations

  • B. J. Government Medical College

    Pune, Maharashtra, 411001, India

  • Baylor Research Institute

    Dallas, Texas, 75204-651, United States

  • Cleveland Clinic - Florida

    Weston, Florida, 33331, United States

  • Hospital for Special Surgery

    New York, New York, 10021, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21224, United States

  • KDH - Kokilaben Dhirubhai Ambani Hospital

    Mumbai, Maharashtra, 400053, India

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29403, United States

  • PGIMER

    Chandigarh, Chandigarh, 160012, India

  • The Universtity of Arizona Arthrtis Center

    Tucson, Arizona, 85724, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • UCLA

    Los Angeles, California, 90095-1670, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.