SKIN DISEASES

This study is testing whether a medication called guselkumab can help heal painful skin ulcers caused by pyoderma gangrenosum, a rare inflammatory skin condition. Seventeen adult participants will receive guselkumab injections every four weeks along with a stable daily dose of pr…

This is the first time researchers are testing the experimental drug BG-A3004 in people. The study aims to check if the drug is safe and how it behaves in the body, first in healthy volunteers and then in patients with immune-related skin conditions like alopecia areata, lichen p…

This study is testing whether Oleogel-S10 gel helps close wounds in people with two types of epidermolysis bullosa (EB), a rare genetic condition that causes fragile, blistering skin. Japanese children and adults with confirmed EB will apply the gel to their wounds for 45 days wh…

This study is testing whether a pill called baricitinib can help regrow hair in children and teenagers with severe alopecia areata, a condition that causes sudden hair loss. About 595 participants aged 6 to 18 will take the pill or a placebo for 36 weeks to see if it's safe and e…

This study is testing a new, non-invasive scanner called OCT Vibrography. The goal is to see if it can safely measure the stiffness of tissues in the eye, skin, and gums. Researchers will compare scans from 90 healthy volunteers and people with an eye condition called keratoconus…

This study aims to build a collection of blood samples and medical information from 800 patients with autoimmune skin diseases like psoriasis, lupus, and eczema. Researchers will analyze these samples to identify biological markers and understand how these diseases develop. The g…

This study aims to understand how often and why skin reactions like redness and itching occur under the dressings that cover implanted chest ports used for chemotherapy. It will follow 500 new chemotherapy patients to measure the problem and look for links to factors like the typ…

This study aims to observe how patients with moderate-to-severe atopic dermatitis (eczema) respond to the medication abrocitinib in real-world, everyday clinical practice. It will follow 200 patients aged 12 and older who are newly prescribed this medication by their doctor. Rese…

This study aims to understand how common eczema treatments, including antibiotics and bleach baths, change the community of bacteria living on the skin. Researchers will observe 130 healthy volunteers and people with moderate-to-severe eczema over one year, collecting skin sample…

This study aims to better understand two specific types of chronic hives triggered by cold or pressure. Researchers will compare 40 people with these hives to people with other hives and healthy volunteers. They will collect skin, blood, and other samples to look for biological m…