New gel could help heal wounds in rare skin disease

NCT ID NCT06917690

Recruiting now Disease control Sponsor: Chiesi Farmaceutici S.p.A. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a gel called Oleogel-S10 on skin wounds in people with inherited epidermolysis bullosa (EB), a condition that causes fragile, blistering skin. The trial includes 6 Japanese children and adults with junctional or dystrophic EB. Participants apply the gel to wounds every few days for 45 days, with follow-up visits every two weeks. The goal is to see if the gel helps wounds close faster and is safe to use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Oleogel-S10 (a topical gel)
What this could lead to: If successful, this gel could become a treatment option to help close and heal skin wounds in people with epidermolysis bullosa, reducing pain and infection risk.
What could go wrong: This is a small, early-phase trial with only 6 participants, so results may not apply to everyone. The gel may not work for all wound types, and side effects are still being studied.

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Conditions

The condition(s) this trial relates to.

Collagen Diseases Congenital Abnormalities connective tissue disorder dystrophic epidermolysis bullosa, dog epidermolysis bullosa epidermolysis bullosa dystrophica hereditary disease junctional epidermolysis bullosa rheumatic disorder Skin Abnormalities skin disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLLAGEN DISEASES CONGENITAL ABNORMALITIES CONNECTIVE TISSUE DISEASE EPIDERMOLYSIS BULLOSA EPIDERMOLYSIS BULLOSA, DYSTROPHIC EPIDERMOLYSIS BULLOSA, JUNCTIONAL GENETIC DISEASES, INBORN JUNCTIONAL EPIDERMOLYSIS BULLOSA SKIN ABNORMALITIES SKIN DISEASES

Contacts and locations

Locations

Fukuoka Children's Hospital - Dermatology
RECRUITING

Fukuoka, Japan
Hokkaido University Hospital
RECRUITING

Sapporo, Japan
Kobe University Hospital
RECRUITING

Kobe, Japan
Kurume University Hospital
RECRUITING

Fukuoka, Japan
Niigata University Medical and Dental Hospital
RECRUITING

Niigata, Japan
Toho University Omori Medical Center
RECRUITING

Ōta-ku, Japan

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