SKIN DISEASES

This early-stage study is testing a new drug called BG-A3004 for the first time in humans. It aims to check the drug's safety in healthy volunteers and in people with immune-related skin diseases. The study will give either one or four doses and follow participants for about 168 …

This study tests a gel called Oleogel-S10 on skin wounds from two types of epidermolysis bullosa (EB), a rare genetic condition that makes skin very fragile. About 6 Japanese children and adults will apply the gel to their wounds at dressing changes for 45 days, with the option t…

This study tests if guselkumab can heal painful skin ulcers in adults with pyoderma gangrenosum, a rare condition. 17 participants will receive the drug and be checked at 6, 16, and 32 weeks. The main goal is complete wound healing by week 32.

This study tests whether baricitinib, a daily pill, can help children aged 6 to 17 with severe alopecia areata (a condition causing patchy or total hair loss). About 595 kids will receive either the drug or a placebo for 36 weeks, with long-term follow-up. The goal is to see if t…

This study follows 200 people aged 12 and older with moderate-to-severe eczema who are starting a new prescription of abrocitinib. Researchers will track how well the drug controls symptoms like itching and rash over 12 months in real-world settings. The goal is to see if the imp…

This study tests whether dupilumab, a drug already used for eczema, can reduce severe itching in people with genetic skin disorders. About 30 participants will receive the drug for up to 104 weeks. The goal is to see if itch improves and if the treatment is safe.

This study looks at how treatments for eczema (atopic dermatitis) change the types and amounts of bacteria on the skin. Researchers will compare skin samples from people with eczema and healthy volunteers over one year. The goal is to understand how treatments affect the skin's m…

This study will track 500 adults starting chemotherapy with a chest port to see how often skin reactions like itching and redness happen at the dressing site. Researchers want to find out what increases the risk of these reactions, such as the type of dressing or the drugs used. …

This study is creating a large collection of blood samples and health data from 800 people with autoimmune skin diseases (like pemphigus, lupus, and psoriasis). The goal is to identify new biomarkers and autoantibodies that could lead to better treatments. Participants provide bl…

This study aims to find biological markers (biomarkers) that can help diagnose and monitor chronic induced urticaria, a condition where specific triggers like cold or pressure cause itchy hives. Researchers will compare 40 participants—including patients with cold urticaria or sy…

This study is testing a new device called OCT Vibrography that uses light and gentle vibrations to measure the stiffness of tissues like the cornea, skin, and gums. Researchers will enroll 90 healthy volunteers to see if the tool is safe and works well. This is not a treatment st…