Rituximab infection risk under the microscope

NCT ID NCT03778840

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study followed 73 people with autoimmune diseases like rheumatoid arthritis or multiple sclerosis who were starting treatment with rituximab. The goal was to track how many developed serious infections and to understand what factors increase that risk. Researchers also looked at whether giving intravenous immunoglobulins could help prevent infections. The findings may help doctors use rituximab more safely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rituximab

What this could lead to

If successful, this could help doctors better predict and prevent serious infections in patients taking rituximab for autoimmune diseases.

What could go wrong

This is an observational study, not a treatment trial. It aims to gather data, not test a new therapy, so it won't directly change care yet.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autoimmune disease Infections

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Claude Huriez, CHU

    Lille, France