Study pits two MG drugs Head-to-Head in everyday practice
NCT ID NCT03490539
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how well two drugs, azathioprine and mycophenolate mofetil, work for people with myasthenia gravis in everyday medical practice. Researchers followed 82 adults with autoimmune MG for 2-3 years, measuring quality of life and side effects. The goal was to provide real-world evidence to help patients and doctors choose the best treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Mycophenolate mofetil (Cellcept) and azathioprine (Imuran)
What this could lead to
If successful, this study could help doctors and patients choose between these two drugs based on real-world effectiveness and side effects.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by patient differences. It is also relatively small (82 participants) and completed, so it provides information but not a definitive answer.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Duke University
Durham, North Carolina, 27710, United States
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London Health Sciences Centre
London, Ontario, N6A5A5, Canada
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Ochsner Clinic Foundation
New Orleans, Louisiana, 70121, United States
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Rush University Medical Center
Chicago, Illinois, 60612, United States
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St. Elizabeth's Medical Center
Brighton, Massachusetts, 02135, United States
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Stanford University
Palo Alto, California, 84303, United States
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University at Buffalo, SUNY
Buffalo, New York, 14202, United States
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University of Alberta Hospital, Faculty of Medicine
Edmonton, Alberta, T6G2G3, Canada
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University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
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University of Rochester Medical Center
Rochester, New York, 14642, United States
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University of Vermont - Larner College of Medicine
Burlington, Vermont, 05401, United States
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Unversity of Miami
Miami, Florida, 33136, United States