New study aims to unlock mysteries of immunotherapy side effects

NCT ID NCT04656873

Completed Knowledge-focused Sponsor: UNC Lineberger Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This study collects medical information and biological samples (blood, urine, stool, etc.) from 32 cancer patients starting or restarting immunotherapy. The goal is to build a research database to better understand why some patients develop immune-related side effects and how to manage them. No new treatments are being tested; it is purely for knowledge gathering.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help doctors predict and better manage immune-related side effects from cancer immunotherapy.
What could go wrong: This is an observational study, not a treatment trial. It is small (32 participants) and aims to build a database for future research, so direct benefits are unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autoimmune disease cancer immune system disorder neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTOIMMUNE DISEASES IMMUNE SYSTEM DISEASES MALIGNANCY

Contacts and locations

Locations

Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill

Chapel Hill, North Carolina, 27599, United States

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