New drug VIS171 tested in humans for first time – could it tame autoimmune disease?
NCT ID NCT05418101
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tested a new drug called VIS171 in 61 people: first in healthy volunteers, then in patients with autoimmune diseases. The main goal was to check safety and how the body processes the drug. No results on whether it actually helps the disease are available yet.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
VIS171
What this could lead to
If this early study shows VIS171 is safe, it could pave the way for a new treatment option for autoimmune diseases.
What could go wrong
This is a very early Phase 1 trial focused on safety, not effectiveness. It is small (61 people) and may fail to show benefit or have unexpected side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ambulatory for Specialized Medical Help - skin and venereal diseases
Sofia, 1407, Bulgaria
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Clinical republican Hospital
Chisinau, MD 2025, Moldova
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Comac Medical Ltd
Sofia, 1612, Bulgaria
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Diagnostic and Consultative Center Convex EOOD
Sofia, 1680, Bulgaria
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MBAL Sveta Sofia
Sofia, 1618, Bulgaria
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New Zealand Clinical Research
Christchurch, 8011, New Zealand
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Radboud University Medical Center
Gelderland, 6525, Netherlands
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UMHAT
Plovdiv, 4002, Bulgaria
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Universitaetsklinikum Bonn AöR
Bonn, 53127, Germany
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Universitätsmedizin der Johannes-Gutenberg-Universität Mainz
Rheinland-Pfalz, 55131, Germany