ATHEROSCLEROSIS

This study tests whether a comprehensive program of lifestyle changes, medication, and special heart scans (PET imaging) works better than standard medical care alone for people with or at high risk for heart disease. Over 1,000 participants were randomly assigned to one of the t…

This study compares two imaging methods during heart stent procedures: ultrasound-guided versus standard X-ray imaging. Researchers want to see if using ultrasound during stent placement leads to better long-term results for people with complex artery blockages. The study involve…

This study aimed to compare two FDA-approved devices that help seal the artery after heart catheterization through the groin. Researchers wanted to see if using both devices together would help patients walk sooner after their procedure compared to using just one device. The tria…

This study aims to understand if bacteria in your gut and mouth are linked to artery plaque and the risk of having a stroke. Researchers will compare 215 people with carotid artery disease to 70 healthy people, checking their blood, diet, and bacteria levels. They want to see if …

This project is creating a large database of heart scan images from 1000 patients who had multiple types of imaging tests. The goal is to collect these images so researchers can study them later to better understand how artery plaque (atherosclerosis) develops and causes heart pr…

This is a long-term observational study that aims to understand how heart and blood vessel diseases develop in people before they show symptoms. It follows over 6,400 healthy men and women from four different ethnic backgrounds, aged 45-84, using regular scans and tests over many…

This study aims to find out why people of South Asian descent have higher rates of heart disease and stroke, even when typical risk factors are accounted for. Researchers are following over 2,300 South Asian adults in the US for several years to identify new causes. The goal is t…

This study aimed to understand how powerful cholesterol-lowering drugs (PCSK9 inhibitors) affect inflammation in the arteries of people with heart disease. Researchers planned to use a special imaging scan to measure inflammation in participants already on standard statin medicat…