Can a supercharged lifestyle program beat standard heart care?
NCT ID NCT00756379
First seen Mar 23, 2026 · Last updated Jun 23, 2026 · Updated 9 times
Summary
This study tests whether a comprehensive program of lifestyle changes (diet, exercise, education) plus aggressive cholesterol-lowering drugs, guided by PET heart scans, can reduce heart attacks and deaths better than standard medical care. Over 1,000 adults with suspected or known coronary artery disease will be followed for 5 years. The goal is to see if this intensive approach improves heart health and is cost-effective.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CORONARY ARTERY DISEASE are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Weatherhead PET Center, Memorial Hermann Hospital TMC
Houston, Texas, 77030, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
comprehensive lifestyle modification program (diet, exercise, education) plus lipid-lowering drugs
What this could lead to
If successful, this could show that an intensive lifestyle and medication program, guided by PET scans, reduces heart attacks and deaths more than standard care.
What could go wrong
This is a single-center study, so results may not apply everywhere. The program is intensive and may be hard for many people to follow long-term.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.