ATHEROSCLEROSIS

This study compares two cholesterol-lowering approaches in about 1,950 adults with chronic kidney disease and heart disease. One group gets a moderate statin plus ezetimibe, the other a high-dose statin alone. The goal is to see if the combination is as good at preventing heart a…

This study tests an experimental drug called YN001 in 456 adults with coronary atherosclerosis (plaque buildup in heart arteries). Participants will receive either YN001 or a placebo by IV, alongside their usual heart medications. The main goal is to see if YN001 reduces non-calc…

This study will see if an artificial intelligence program called CaRi-Heart can find inflammation in heart arteries from standard CT scans. Researchers want to know if this extra information helps doctors make better treatment decisions, like starting medications or referring to …

This study will examine 100 adults on hemodialysis to see how traditional heart risk factors (like high blood pressure and diabetes) and dialysis-specific factors (like treatment length) relate to the thickness of the carotid artery wall. The goal is to better understand why hear…

This study will use a safe, painless neck ultrasound to look for early signs of artery hardening in 96 adults who have both type 2 diabetes and moderate chronic kidney disease. The goal is to find out how common hidden artery disease is in this high-risk group and how it relates …

This study looks at 70 children and teens with juvenile lupus to see if they have early signs of heart disease. Researchers will use ultrasound to measure the thickness of the carotid artery wall and compare it to healthy children. The goal is to understand how lupus and its trea…