ATHEROSCLEROSIS

This study tested whether ticagrelor, a stronger anti-clotting drug, reduces heart muscle damage compared to standard clopidogrel in 180 patients with hardened heart arteries. All patients took aspirin and either ticagrelor or clopidogrel before a procedure that grinds away calci…

This study tested whether delivering the drug paclitaxel directly to the leg artery during a standard balloon procedure can help keep the artery from narrowing again. 27 adults with blocked leg arteries (peripheral artery disease) took part. The goal was to see if this approach i…

This study tested a new medicine called olezarsen in about 1,500 adults with very high triglycerides (a type of blood fat) who also had heart disease or were at high risk for it. The goal was to see if olezarsen could lower triglyceride levels more than a placebo over 25 weeks. P…

This early-phase study tested whether injecting donor stem cells into the leg before amputation could prevent wound complications and reduce the need for further surgery. 81 adults aged 40-90 with severe leg artery disease received the injections. The main goal was to check safet…

This study tested a digital quality improvement program to help doctors better manage LDL (bad) cholesterol in patients with heart disease. Over 1,400 adults in Brazil with established cardiovascular disease participated. The program used smartphone tools to improve treatment and…

This study looked at whether colchicine, a drug used for gout, can reduce inflammation in the arteries of people with diabetes or pre-diabetes who recently had a heart attack or stroke. Inflammation is a key driver of artery plaque buildup, which can lead to more heart problems. …

This study looked at whether the flu vaccine can reduce inflammation in 47 older adults with stable coronary artery disease. Researchers measured blood markers of inflammation before and after vaccination. The goal was to see if the vaccine might lower heart risks by calming the …

This study looked at how well the ELUVIA drug-coated stent works in real-world patients with blocked arteries in the leg. About 291 adults received the stent and were followed for two years. Researchers measured changes in quality of life and walking ability to see if the stent h…

This study created a 'Stroke Awareness Team' to teach the Oneida Nation about stroke risks and healthy living. About 120 people at high risk for stroke took part in health events and education sessions. The goal was to lower stroke rates by improving blood pressure, cholesterol, …

This study examined why some people still have ischemic strokes while taking blood thinners called NOACs. Researchers looked at 91 Chinese patients with atrial fibrillation to understand causes and how well they followed their medication plan. The goal was to find preventable fac…

This study looked at 320 people with atherosclerosis (hardening of the arteries) to see how the disease changes over 10 years. Researchers checked genetic, blood, and ultrasound factors to find links to heart attacks, strokes, and leg problems. The goal was to better understand w…

This study checked if newer psoriasis medications (IL17/23 inhibitors) can also improve heart health by measuring artery stiffness. Researchers followed 66 adults with moderate-to-severe psoriasis for one year, comparing those on the new drugs to those on standard treatments. The…

This study looked at whether vitamin D levels in the blood are related to early signs of artery hardening (atherosclerosis) in people on dialysis. Researchers measured vitamin D and artery thickness in 90 adults who had been on dialysis for at least 6 months. The goal was to see …

This study looked at whether patients who were hospitalized for a heart attack, stroke, or other heart-related event were prescribed the recommended cholesterol-lowering medications when they left the hospital. Researchers observed 129 patients to see how well doctors followed of…

This study looked at whether certain blood markers can predict serious heart problems like heart attack or death after a stent procedure. Researchers measured two types of cells in the blood that reflect blood vessel injury and healing. They followed 170 adults for up to a year t…

This study looked at how a high-dose fish oil supplement (E-EPA) affects cholesterol and blood fats in 68 healthy adults aged 18-65. Participants took the supplement daily for one month while eating normally. Researchers measured changes in LDL cholesterol stickiness and blood tr…

This study looked at how excess belly fat relates to the buildup of fatty deposits in arteries, known as atherosclerosis, which can lead to heart attacks. Researchers used MRI and CT scans to measure fat and plaque in 357 healthy adults aged 35-65. The goal was to better understa…

This study looked at a small molecule called microRNA-210 in 230 people with peripheral artery disease (PAD), a condition where leg arteries become blocked. Researchers measured its levels and linked them to walking ability and muscle health. The goal was to better understand the…