ATHEROSCLEROSIS

This small study tested whether getting a flu shot directly reduces harmful inflammation in people with stable coronary artery disease. Researchers gave 47 participants the vaccine either right away or after a one-month delay, then measured inflammation markers in their blood. Th…

This study tested whether a new drug called olezarsen could safely lower high levels of triglycerides, a type of fat in the blood linked to heart disease. About 1,500 adults with high triglycerides and either existing heart disease or a high risk for it received either the drug o…

This study tested whether a newer blood-thinning drug (ticagrelor) works better than a standard one (clopidogrel) during a procedure to clear severely hardened heart arteries. Researchers enrolled 180 patients with stable heart disease to see if the newer drug reduces heart muscl…

This early-stage study tested whether injecting donor stem cells into the leg muscles of patients about to have a major amputation could help prevent serious wound complications after surgery. The main goal was to check if the injections were safe. Researchers also wanted to see …

This study looked at whether patients who were hospitalized for serious heart or stroke events received the recommended cholesterol-lowering medications when they left the hospital. Researchers followed 129 patients to see if doctors prescribed drugs proven to significantly lower…

This study tested whether a community health program could prevent strokes in Native Americans at high risk. Researchers trained local health coaches to provide education and intensive lifestyle coaching to 120 tribal members over two years. They measured changes in stroke risk f…

This study aimed to understand how a tiny molecule in the body, called microRNA-210, is involved in the stress and energy problems that occur in the muscles of people with peripheral artery disease (PAD). Researchers compared 180 patients who had a procedure to improve blood flow…

This study aimed to see if newer psoriasis medications (IL17 or IL23 inhibitors) improve markers of artery stiffness and heart health over one year. It observed 66 patients with moderate-to-severe psoriasis who were already starting these treatments. The main goal was to measure …

This completed study looked for a connection between vitamin D levels in the blood and early signs of heart disease in people receiving long-term dialysis. Researchers enrolled 90 adult patients to measure their vitamin D and check for artery hardening. The goal was to gather inf…

This study looked at why some people who take newer blood thinners (NOACs) for an irregular heartbeat still have strokes. Researchers reviewed the medical records of 91 Chinese patients to understand the causes, patient characteristics, and treatment outcomes. The goal was to gat…

This study aimed to understand how a specific fish oil ingredient (EPA) might protect the heart. Healthy volunteers took a daily EPA supplement for a month. Researchers analyzed their blood to see if EPA changed the properties of 'bad' cholesterol (LDL) and other fats, looking fo…

This study aimed to better understand how excess belly fat relates to the buildup of fatty plaques in arteries, which can lead to heart attacks. Researchers used MRI and CT scans to measure fat distribution and artery plaque in 357 healthy adults aged 35-65. The goal was to gathe…

This study aimed to understand how atherosclerosis (hardening of the arteries) develops over time in different parts of the body, like the heart, brain, and legs. Researchers followed 320 patients for 10 years, checking for major events like heart attacks and strokes, and using u…