Marathoners' hearts under the microscope: is that plaque dangerous?
NCT ID NCT07625488
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study follows 250 male endurance athletes who were part of an earlier study to see how their heart arteries have changed over time. Researchers will use CT scans and AI to examine plaque buildup and determine if it is stable and harmless or likely to cause heart attacks. The goal is to understand why some athletes develop calcium deposits in their heart arteries despite being very fit.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could clarify whether high levels of endurance exercise cause dangerous or harmless plaque buildup in athletes' hearts.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to non-athletes or women.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CORONARY ARTERY DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Radboud University Medical Center
Nijmegen, 6525 GA, Netherlands
-
University Medical Center Utrecht
Utrecht, 3584 CX, Netherlands