AMPUTATION

This study tested a new type of prosthetic leg for people who have lost a leg below or above the knee. The smart leg uses sensors to detect movement and gives gentle vibrations to help the user walk more naturally. Eight experienced prosthetic users took part to see if the device…

This study tested a special vacuum dressing called PREVENA on 272 adults who had a leg amputated. The goal was to see if it could reduce wound problems like infection, fluid buildup, or skin reopening. Participants were randomly assigned to get either the special dressing or stan…

This study tested a new type of bionic leg for people with below-knee amputations. The leg uses special muscle sensors to let users control the foot's movement and feel its position. Researchers compared 14 participants who had the new surgery with those who had standard amputati…

This study tested hand transplants in 7 people who lost both forearms. The goal was to see if the brain could adapt to the new hands and improve daily life. Participants had to take lifelong anti-rejection medication, so this is a disease control approach, not a cure.

This early-phase study tested whether injecting donor stem cells into the leg before amputation could prevent wound complications and reduce the need for further surgery. 81 adults aged 40-90 with severe leg artery disease received the injections. The main goal was to check safet…

This study looked at whether adding the antibiotic rifampin to usual treatment can prevent foot or leg amputations in people with diabetes who have a bone infection. Over 800 adults took part. The goal was to see if the combination works better than standard care alone to keep pa…

This study tested a new way of coordinating care for rural patients with diabetic foot ulcers, who are at higher risk of major leg amputation. The model brought together rural clinics and specialists to ensure patients got the right vascular and infection care quickly. Researcher…

This study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures how well a person can move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or amput…

This study tested whether medicated cloths (glycopyrronium) could reduce excessive sweating at the amputation site in 13 people with limb loss. Participants used either the medicated cloth or a placebo for 4 weeks, then switched after a break. The goal was to see if less sweating…

This study tested a new powered knee (Mobili Knee) in 6 people who use a leg prosthesis. Participants performed walking and balance tests with their usual knee and then with the new knee. The goal was to see if the powered knee improves basic mobility and balance.

This study tested a new microprocessor-controlled prosthetic knee in 11 active amputees. Participants used the new knee for 4 weeks at home, and researchers measured satisfaction with stair and ramp descent, walking, and overall mobility. The goal was to see if the new knee perfo…

This study tested a new type of bionic knee for people who have lost a leg. 14 adults who already use a similar knee tried the new device to see if it made walking down stairs more satisfying. The goal was to compare the new knee to their usual one.

This study tested whether an adjustable prosthetic socket is more comfortable and improves mobility compared to a standard socket. 29 adults with a leg amputation who already use a prosthesis took part. Researchers measured comfort, balance, walking speed, and quality of life to …

This study tested a new powered knee (Power Knee) in 17 people with leg amputations to see if it makes walking less tiring than standard microprocessor knees. Participants walked, climbed stairs, and did daily tasks with both knees to compare effort and mobility. The goal was to …

This study tested a new way to create prosthetic sockets using a digital system that scans the leg while the person stands (weight-bearing). The goal was to see if this method leads to a better fit, more comfort, and improved skin health compared to traditional non-weight-bearing…

This study looked at whether prosthetists (the specialists who fit artificial limbs) can screen for common health problems like depression, nerve damage, and poor blood flow during routine visits. 70 people with a leg amputation took part. Half got standard care, and the other ha…

This study tested a new hybrid pump that creates a vacuum to help hold a prosthetic limb in place. 12 people with amputations walked in a lab to see if the pump improved socket comfort and mobility. The goal was to check if the pump works well during walking.

This study looked at how satisfied people in Gaza who use a prosthetic leg are with their device and their overall quality of life during the 2023 war. Researchers surveyed 128 adults who had used a prosthetic leg for at least six months. The goal was to understand their needs an…

This study looked at 13 people with a leg amputation who use a prosthetic foot. Researchers wanted to find out which type of prosthetic foot helps them walk better when carrying infants, toddlers, or other loads. Participants walked with different prosthetic feet while carrying v…

This study looked at how people with a leg amputation (below or above the knee) use their muscles and adjust their body to stay balanced when the surface they stand on moves suddenly. Researchers measured muscle activity and body movements in 29 adults who had used a prosthetic l…

This study looked at why people swing their arms when they walk, especially in people with conditions like multiple sclerosis, stroke, or Parkinson's disease. Researchers had 25 participants walk on a special treadmill to measure how arm movement relates to body motion. The goal …

This study looked at how well a low-cost prosthetic foot works compared to standard ones for people who have lost a leg below the knee. Six participants performed balance tests, walking tasks, and jumps in a lab. The goal was to see if the cheaper option could provide similar mov…

This observational study looked at 26 adults with a below-knee amputation and healthy volunteers to understand how amputation impacts core function and endurance. Participants performed tests measuring core strength, balance, joint position sense, and walking speed. The goal was …

This study tested a new type of prosthetic foot designed for people with below-knee amputation who have longer residual limbs. The foot is low-profile but aims to provide better flexibility and energy return, similar to taller prosthetic feet. Six adults who already use a low-pro…

This study tested a new surgical method for below- and above-knee amputations to help people use advanced prosthetic limbs more naturally. Researchers worked with 50 adults who needed a leg amputation due to injury, birth defects, or arthritis. The goal was to see if the new tech…

This study looked at how powered ankle prostheses change the pressure inside the prosthetic socket and the health of the residual limb in people with below-knee amputations. Six adults who already use a passive prosthesis walked on level ground while researchers measured socket p…