AMPUTATION

This study tested whether transplanting two donor hands could restore function for people with double forearm amputations. Researchers followed 7 adult patients to see how their brains adapted to controlling the new hands. The goal was to offer an alternative to prosthetics by re…

This study tested whether adding the antibiotic rifampin to standard treatments could help prevent foot and leg amputations in diabetic patients with serious bone infections. Researchers followed 843 veterans with diabetes and foot bone infections, giving half rifampin and half a…

This study tested a new way to perform leg amputations. The goal was to create a better biological connection point in the remaining limb to allow for more intuitive control of advanced prosthetic legs. Researchers worked with 50 adults needing a leg amputation to see if this new…

This early-stage study tested whether injecting donor stem cells into the leg muscles of patients about to have a major amputation could help prevent serious wound complications after surgery. The main goal was to check if the injections were safe. Researchers also wanted to see …

This study tested a new approach to help people with below-knee amputations control a bionic leg more naturally. Researchers compared a special surgical technique that reconnects muscles in the residual limb to a standard amputation. The goal was to see if this new method, combin…

This study tested whether a special vacuum-sealed dressing called PREVENA could prevent wound complications after leg amputation surgery. Researchers compared this dressing to standard wound care in 272 adults who had above- or below-knee amputations. They tracked whether the spe…

This study tested a new computer-controlled prosthetic knee to see if it works better than existing smart knees. Fourteen people with above-knee amputations tried the new knee for three weeks and compared it to their usual device. Researchers measured how satisfied people felt wh…

This study tested whether a medicated cloth (Qbrexza) could reduce excessive sweating where a prosthetic limb attaches. Thirteen people with limb amputations used either the active cloth or a placebo for four weeks, then switched, to see if it improved sweat control and how well …

This study tested a new, smart prosthetic leg for people with above- or below-knee amputations. The device uses sensors to read the user's muscle signals and has motorized knee and ankle joints that actively help with walking. Researchers checked if the advanced prosthesis was sa…

This study tested a new computerized prosthetic knee to see if it improved daily life for people with leg amputations. Eleven participants used the new knee for four weeks at home. Researchers measured if it helped with walking, using stairs and ramps, and boosted confidence comp…

This study tested different prosthetic feet to see which one helps people with below-knee amputations walk better while carrying heavy loads. Thirteen participants walked on a treadmill while carrying a weighted pack to simulate holding a child or a heavy bag. Researchers measure…

This small study tested a new, thinner prosthetic foot designed for people with below-knee amputations who have longer remaining limbs. The goal was to see if this new foot could store energy and provide a comfortable walking experience similar to bulkier prosthetics. Six partici…

This study tested a new powered prosthetic knee to see if it makes walking and daily activities easier for people with above-knee amputations. Seventeen participants tried the new 'Power Knee' and their own microprocessor-controlled knee in a crossover design. Researchers measure…

This small study tested a new powered, computer-controlled knee prosthesis (the Mobili Knee) on six adults with above-knee leg amputations. The goal was to see if the new knee improved their walking speed, balance, and ability to do daily tasks compared to their usual prosthetic …

This study tested a new digital system for creating prosthetic sockets while the user is standing and bearing weight. It compared this new method to the traditional way of scanning a limb while sitting. The goal was to see if the new approach leads to a better-fitting, more comfo…

This study aimed to understand how losing a lower leg affects core muscle function, endurance, balance, and walking. Researchers compared 26 adults with a below-knee amputation to adults without an amputation through a series of physical tests. The goal was to gather knowledge to…

This study aimed to understand how advanced, powered ankle prosthetics affect the pressure inside the socket and the health of the skin on the residual limb. Researchers measured six adults with below-knee amputations while they walked using different types of prosthetic ankles. …

This study tested whether having prosthetists screen for common hidden health problems during routine visits could improve care for people after a leg amputation. Seventy patients were randomly assigned to receive either standard care or standard care plus extra screenings for is…

This study aimed to understand why people swing their arms while walking and how this movement is connected to balance and energy use. Researchers observed 25 people, including healthy individuals and those with conditions like stroke, Parkinson's, or multiple sclerosis, while th…

This study aimed to understand how people with below-knee or above-knee amputations keep their balance when a platform they're standing on moves unexpectedly. Researchers compared 29 adults with leg amputations to healthy individuals, measuring their muscle activity and body move…

This study aimed to see if a new, lower-cost prosthetic foot works as well as the standard models for people with a below-knee amputation. Six participants performed walking, balance, and jumping tests indoors and outdoors while wearing each type of foot. The goal was to compare …

This study tested a Turkish version of a questionnaire called the Johns Hopkins In-Room Independence Scale. Researchers gave the questionnaire to 100 adult volunteers with various conditions to see if it reliably measures how well a person can move and care for themselves in thei…

This study aimed to understand if adjustable prosthetic sockets are more comfortable and improve mobility compared to standard sockets. Researchers tested 29 adults with above-knee amputations, having them try both their usual socket and different adjustable designs. They measure…