AMPUTATION
Clinical trials for AMPUTATION explained in plain language.
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New exercise combo could boost fitness in amputee soccer players
Disease control OngoingThis study looks at whether a specific type of exercise, called PNF-based upper extremity strengthening combined with core stabilization, can improve physical fitness in amputee football players. Fourteen players with a lower limb amputation will be split into two groups: one doi…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: Uskudar University • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Magnetic beads could give amputees Mind-Controlled bionic legs
Disease control OngoingThis study tests a new system that uses magnetic beads implanted in leg muscles to help people with below-knee amputations control a bionic ankle-foot prosthesis. The beads track muscle movement in real time, sending signals to a robotic leg. Up to 7 participants will receive the…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Nerve cap aims to ease pain after limb loss
Symptom relief OngoingThis study tests a special nerve cap (Axoguard Large-Diameter Nerve Cap) in 15 adults who have had a limb injury or amputation. The cap is placed over the cut nerve end to protect it and may help reduce chronic nerve pain. The goal is to see if the cap is safe and works well befo…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: Axogen Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New smart socket aims to get amputees moving again
Symptom relief OngoingThis study tests a new type of prosthetic socket and liner designed to better distribute pressure on the remaining limb. Combined with an exercise program, the goal is to help people who lost a leg due to diabetes walk more and improve their health. About 38 participants who alre…
Matched conditions: AMPUTATION
Phase: PHASE2 • Sponsor: Spaulding Rehabilitation Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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New liners aim to stop sweaty prosthesis woes
Symptom relief OngoingThis study compares three different prosthetic liners designed to handle sweating inside an artificial leg. About 180 people with a below-knee amputation who currently have sweat problems will test each liner. The goal is to see which liner helps them feel more stable, secure, an…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: VA Puget Sound Health Care System • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Smart sensors could revolutionize rehab for amputees
Symptom relief OngoingThis study tests whether smartphone and wearable sensors can help create personalized mobility plans for people who use lower-limb prostheses. Researchers will analyze sensor data along with walking tests and interviews to identify physical or psychological barriers to using the …
Matched conditions: AMPUTATION
Phase: NA • Sponsor: Shirley Ryan AbilityLab • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Shock-Absorbing prostheses may protect skin in amputees with diabetes
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how skin temperature and blood flow change in people with a leg amputation, especially those with diabetes. Researchers will test two types of prosthetic legs—rigid and shock-absorbing—to see which one keeps the skin cooler and healthier. Sixty participants wi…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Can a bionic hand feel real? study aims to find out
Knowledge-focused TerminatedThis study aimed to help people with upper limb amputations feel their prosthetic hand as part of their own body. Researchers planned to use nerve stimulation to create touch and position sensations. The study was withdrawn before any participants were enrolled, so no results are…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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New training aims to fix uneven walking in leg prosthesis users
Knowledge-focused OngoingThis study tests whether a 40-week biofeedback training program can help people with a leg prosthesis (attached directly to the bone) walk with more equal weight on both legs. Fifteen participants will either receive the training or standard education. Researchers will measure fe…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Ultrasound could give amputees a better grip on prosthetics
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing a new type of prosthetic hand that uses ultrasound to read muscle movements, instead of the usual electrical sensors. The goal is to see if this makes the hand easier and more natural to control. Sixteen people with below-elbow amputations will compare the n…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: George Mason University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Amputation for pain: how long until patients walk again?
Knowledge-focused OngoingThis study reviews the medical records of 20 adults who had a limb amputated to relieve severe, long-lasting pain from complex regional pain syndrome (CRPS). Researchers want to measure how many days pass between the amputation and when patients first use a functional prosthetic …
Matched conditions: AMPUTATION
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Spinal stimulation sensation study pulled before start
Knowledge-focused TerminatedThis study was designed to explore what kinds of feelings (like touch or tingling) could be created by electrically stimulating the spinal cord in people with amputations who experience phantom limb pain. Researchers planned to work with patients who already had a spinal cord sti…
Matched conditions: AMPUTATION
Sponsor: Lee Fisher, PhD • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC