AMPUTATION
Clinical trials for AMPUTATION explained in plain language.
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New powered knee aims to help amputees walk farther and more easily
Symptom relief Not yet recruitingThis study will compare a new powered prosthetic knee called the Bio-Leg to the current standard C-Leg in 12 adults who have lost a leg above the knee. Participants will use their own C-Leg first, then switch to the Bio-Leg for 4-6 weeks. Researchers will measure how far they can…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: University of Florida • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New smart foot could help veterans walk hills safely
Symptom relief Not yet recruitingThis study tests a new prosthetic foot called the Slope Adaptive Foot (SAF) that automatically adjusts to slopes and uneven ground. Thirty veterans with below-knee amputations will try both the SAF and a standard hydraulic foot to see which one improves their ability to take part…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Leg amputation level linked to chronic back pain in veterans
Knowledge-focused Not yet recruitingThis study follows 300 adults with combat-related lower limb amputations to see how the level of amputation (below knee, above knee, or both legs) relates to chronic low back pain. Researchers will measure pain intensity, disability, and rehabilitation progress over time. The goa…
Matched conditions: AMPUTATION
Sponsor: Ukrainian Society of Regional Anesthesia and Pain Therapy • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Long evacuation times linked to PTSD in war amputees?
Knowledge-focused Not yet recruitingThis study follows 300 Ukrainian veterans who lost a limb in combat to see if longer evacuation times or extended tourniquet use increase the risk of developing PTSD. Participants will be monitored for 18 months using PTSD symptom questionnaires. The goal is to identify factors t…
Matched conditions: AMPUTATION
Sponsor: Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New device aims to take the guesswork out of prosthetic fit
Knowledge-focused Not yet recruitingThis study tests a new, non-invasive device that attaches to the outside of a prosthetic leg socket to measure how well it fits. Poor socket fit can cause pain, skin problems, and reduced mobility. The device tracks movement and accuracy as users perform a simple task, aiming to …
Matched conditions: AMPUTATION
Phase: NA • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Could a simple silicone toe divider prevent foot ulcers after amputation?
Knowledge-focused Not yet recruitingThis study looks at whether a moldable silicone toe divider (Otoform) can help people with diabetes who have had a lesser toe amputated. Researchers want to see if it is possible to run a larger trial by testing how well patients accept the device and how it affects walking and f…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: University of Huddersfield • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Could a light zap stop infections in bionic limb patients?
Knowledge-focused Not yet recruitingThis study tests whether a special light treatment can help prevent infections in people with bone-anchored prostheses (artificial limbs attached directly to the bone). Ten participants will apply a medicated cream to the skin where the metal rod comes out, then use a light devic…
Matched conditions: AMPUTATION
Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Can talking to someone Who's been there help trauma survivors heal?
Knowledge-focused Not yet recruitingThis study tests a new peer support program for adults recovering from serious injuries like car crashes, burns, or amputations. The program pairs survivors with trained peers who have been through similar experiences, offering support from hospital to home. The goal is to see if…
Matched conditions: AMPUTATION
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC