Can a medicated cloth stop prosthetic sweating woes?

NCT ID NCT04924036

Completed Symptom relief Sponsor: University of Utah Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether a medicated cloth (glycopyrronium) could reduce excessive sweating at the amputation site in 13 limb amputees. Participants used either the active cloth or a placebo for four weeks, then switched after a washout period. The goal was to see if less sweating would improve how well the prosthetic fits and feels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: glycopyrronium cloths (Qbrexza)
What this could lead to: If it works, this could offer a simple topical treatment to reduce sweating at amputation sites, helping prosthetics fit better and improving comfort.
What could go wrong: This is a small, early-phase trial with only 13 participants, so results may not apply widely. The treatment may not work for everyone, and side effects like skin irritation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hyperhidrosis hyperhidrosis palmaris ET plantaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMPUTATION HYPERHIDROSIS

Contacts and locations

Locations

University of Utah MidValley Dermatology

Murray, Utah, 84107, United States

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