Laser zaps sweat glands in tiny hyperhidrosis trial

NCT ID NCT04178161

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tested a laser treatment for people with excessive sweating (hyperhidrosis). The approach used a dye to mark sweat glands, then a special laser to destroy them. Only 2 people were enrolled, and the study was terminated early, so we have very little data on whether it works or is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Laser treatment (fractional erbium laser) combined with methylene blue iontophoresis

What this could lead to

If it works, this could point toward a minimally invasive treatment for excessive sweating without long-term medication.

What could go wrong

This was a very early, tiny trial (only 2 participants) that was terminated, so results are extremely limited. The procedure may not be effective or safe for broader use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hyperhidrosis hyperhidrosis palmaris ET plantaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital - Wellman Center for Photomedicine

    Boston, Massachusetts, 02114, United States