Botox injections could tame painful skin disease
NCT ID NCT05403710
First seen Jun 25, 2026 · Last updated Aug 07, 2026 · Updated 2 times
Summary
This study is testing whether Botox injections can reduce inflammation in people with hidradenitis suppurativa (HS), a chronic skin condition that causes painful lumps. Researchers believe that blocking certain nerve signals may calm the immune response. The study will enroll 20 adults with HS and examine skin immune cells before and after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Botulinum toxin (Botox)
- What this could lead to
- If it works, this could point toward a new treatment option for hidradenitis suppurativa, a painful skin condition.
- What could go wrong
- This is a very small, early-phase study with only 20 participants. It is testing a theory, not a proven treatment, and may not lead to a widely available therapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
University of Massachusetts Chan Medical School
RECRUITINGWorcester, Massachusetts, 01605, United States
Contact Email: •••••@•••••
More trials for these conditions
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- Head-to-Head: which pill tames hidradenitis suppurativa best?
- Skin disease evolution under the microscope: a 17-Year look at what drives severity
- Could early treatment tame a painful skin condition?
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- New pill shows promise for controlling painful skin condition in long-term trial