Could childhood trauma fuel skin inflammation?

NCT ID NCT05507125

Recruiting now Knowledge-focused Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This study investigates how inflammatory genes are regulated in people with hidradenitis suppurativa (HS), a chronic skin condition causing painful lumps. Researchers will compare inflammatory markers in HS patients versus healthy controls. An optional sub-study explores whether childhood trauma influences HS development. The goal is to better understand the disease mechanisms, which could inform future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could uncover new targets for treating hidradenitis suppurativa and highlight the role of early-life stress in inflammatory skin disease.
What could go wrong: This is an observational study, so it won't directly test a treatment. The findings may not lead to new therapies, and the link between childhood trauma and HS is still uncertain.

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Conditions

The condition(s) this trial relates to.

hidradenitis suppurativa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIDRADENITIS SUPPURATIVA

Contacts and locations

Locations

Whitaker Clinic
RECRUITING

Birmingham, Alabama, 35294, United States

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