HIDRADENITIS SUPPURATIVA

This early-stage study is testing a new drug called HB0043 in adults with moderate to severe hidradenitis suppurativa (HS), a painful chronic skin condition. The main goal is to check the drug's safety and see if it can reduce the number of painful skin lesions. Participants will…

This study is testing whether an oral medication called remibrutinib can safely reduce painful skin lesions in people with moderate-to-severe hidradenitis suppurativa (HS). About 555 participants aged 12 and older will take either one of two doses of the drug or a placebo pill fo…

This study is testing a topical foam called roflumilast to see if it can help control hidradenitis suppurativa, a chronic skin condition that causes painful lumps. Ten adults with the condition will apply the foam daily for four months, either alone or added to their current trea…

This study is testing whether an oral medication called remibrutinib can safely reduce painful skin lesions in people with moderate to severe hidradenitis suppurativa (HS). About 555 participants aged 12 and older will take either one of two doses of the drug or a placebo pill fo…

This study is testing a drug called sonelokimab in teenagers with a painful, chronic skin condition called hidradenitis suppurativa (HS). It aims to see how the drug behaves in the body and how safe it is for adolescents over 24 weeks. The study will also check if the treatment h…

This large, late-stage study is testing whether an investigational drug called lutikizumab can help control the painful lumps and sores caused by moderate-to-severe hidradenitis suppurativa (HS). About 1280 adults and adolescents with HS will receive either the drug or a placebo …

This early-stage study is testing the safety of a cream called ruxolitinib for people with hidradenitis suppurativa, a chronic inflammatory skin disease. It will enroll 24 adults and adolescents to see what side effects occur when the cream is applied to a large area of the skin.…

This study is monitoring the safety and real-world effectiveness of an already-approved drug called Cosentyx (secukinumab) in Korean patients. It will follow 76 people with moderate-to-severe hidradenitis suppurativa (a painful skin condition), pediatric plaque psoriasis, or juve…

This study aims to see how well the drug secukinumab works for people with moderate-to-severe hidradenitis suppurativa (HS) in real-world Canadian clinics. It will follow 142 adult patients newly prescribed this medication to track changes in their disease severity, side effects,…

This study aims to see how well the drug secukinumab works for adults with moderate to severe hidradenitis suppurativa (HS) in real-world medical settings. It will follow 300 patients in Russia who are already starting this treatment as part of their normal care. Researchers will…

This study is testing an investigational drug called brivekimig for people with moderate to severe hidradenitis suppurativa (HS), a chronic inflammatory skin condition. It aims to see if different doses of the drug can safely reduce painful skin lumps and tunnels and improve qual…

This study aims to understand how the drug bimekizumab behaves in the body and how safe it is for teenagers with moderate to severe hidradenitis suppurativa (HS), a painful chronic skin condition. It will enroll about 40 participants aged 12 to 18 who have not responded well to p…

This study is testing whether a daily oral pill called ritlecitinib can safely reduce painful skin lumps in adults with moderate to severe hidradenitis suppurativa (HS), a chronic inflammatory skin disease. The 240 participants, whose HS did not improve with prior antibiotic trea…

This study is testing an investigational oral medication called zasocitinib for adults with moderate to severe hidradenitis suppurativa (HS), a chronic and painful skin condition. For the first 4 months, participants will be randomly assigned to receive either the study drug or a…

This study is testing whether Botox injections can reduce inflammation in painful hidradenitis suppurativa skin lesions. Researchers believe blocking nerve signals with Botox might calm the immune system's overreaction. They will enroll 20 adults with the condition to receive inj…

This study is testing whether a cream called ruxolitinib can safely reduce painful lumps and sores for people with hidradenitis suppurativa (HS), a chronic inflammatory skin condition. About 550 participants with mild to moderate HS will apply either the active cream or a placebo…

This study is testing a new drug called SAR445399 to see if it can reduce painful skin lumps and improve quality of life for adults with moderate to severe hidradenitis suppurativa (HS). Researchers will compare two different doses of the drug against a placebo (inactive substanc…

This study is testing whether a cream containing the drug ruxolitinib can safely reduce painful skin lumps and abscesses in people with hidradenitis suppurativa (HS). About 400 participants with mild to moderate HS will apply either the active cream or a placebo cream to see whic…

This study is testing whether the drug upadacitinib can help control moderate-to-severe hidradenitis suppurativa (HS), a painful inflammatory skin condition, in people who haven't responded well to previous biologic treatments. About 1,328 adult and adolescent participants worldw…

This study aims to understand the physical activity challenges faced by people with hidradenitis suppurativa (HS), a chronic skin condition. Researchers will design and test a special exercise program for 50 adults with HS to see if it can improve their strength, walking ability,…

This study aims to understand how a medication called secukinumab affects the daily lives and satisfaction of people with moderate to severe hidradenitis suppurativa (HS), a painful skin condition. Researchers will follow 60 patients in the United Arab Emirates for 24 weeks, coll…

This study aims to learn more about hidradenitis suppurativa (HS), a painful and poorly understood skin condition. Researchers will observe 1,000 people with HS and some healthy volunteers to track how the disease changes over time and look for biological clues. The goal is to ga…

This study aims to understand how three skin conditions—alopecia areata (hair loss), vitiligo (skin depigmentation), and hidradenitis suppurativa (painful skin lumps)—affect people's daily lives and quality of life. It will survey nearly 2,800 adolescents and adults with moderate…

This study aims to better understand hidradenitis suppurativa (HS), a painful and poorly understood skin condition. Researchers will collect health information and biological samples from 3,000 people with HS over time. The goal is to learn what causes HS, how it progresses, and …

This study aims to collect and store blood, skin, and swab samples from patients with and without certain skin conditions. The goal is to create a resource for future research to better understand how diseases like hidradenitis suppurativa work. It involves 175 participants who a…

This early pilot study is exploring a new idea: whether swallowing capsules containing healthy gut bacteria from a donor can change a person's gut microbiome and potentially help with the painful skin condition hidradenitis suppurativa (HS). Researchers will enroll 16 adults with…

This study is creating a registry to collect information on the safety and healing results when surgeons use Myriad™ devices during various soft tissue reconstruction surgeries. It will enroll about 800 adults who are already scheduled for surgery where their doctor plans to use …

This study aims to measure how much of the medication bimekizumab (Bimzelx®) passes into breast milk. It will enroll 20 breastfeeding mothers who are already using this drug to treat conditions like psoriasis or arthritis. Researchers will collect breast milk samples over several…

This study is creating a large registry of patients with conditions like eczema, psoriasis, and alopecia areata to track how treatments work in real-world settings. Researchers will follow 15,000 adults and children over time to understand treatment safety, effectiveness, and how…