HIDRADENITIS SUPPURATIVA

This study tests a daily pill called ritlecitinib for people with moderate to severe hidradenitis suppurativa (HS), a condition causing painful red skin lumps. About 240 adults who haven't been helped by antibiotics will receive either the drug or a placebo for 16 weeks. Research…

This study follows 250 Italian adults with moderate to severe hidradenitis suppurativa (HS) who are starting secukinumab. Researchers will track how well the drug reduces skin abscesses and tunnels over time, as well as treatment patterns and healthcare costs. The goal is to unde…

This early study tests whether taking a capsule of healthy gut bacteria (microbiota transplant) can change the gut microbiome and help treat hidradenitis suppurativa, a chronic skin condition causing painful boils. Sixteen adults with the disease will receive the capsules and be …

This study tests an experimental drug called remibrutinib in 555 people aged 12 and older with moderate to severe hidradenitis suppurativa (HS), a condition causing painful boils and tunnels under the skin. Participants will receive one of two doses of the drug or a placebo for 6…

This study tests a new drug called SAR445399 for people with moderate to severe hidradenitis suppurativa (HS), a chronic skin condition causing painful lumps. About 144 adults will receive either the drug or a placebo for 32 weeks to see if it reduces abscesses and inflammation. …

This study looks at how well secukinumab works for people with moderate-to-severe hidradenitis suppurativa (a chronic skin condition causing painful lumps) in everyday Canadian clinics. About 142 adults who are already prescribed secukinumab by their doctor will be followed for 1…

This study tests a daily pill called upadacitinib for people with moderate to severe hidradenitis suppurativa (HS) who haven't improved with other treatments. About 1,328 adults and teens will receive either the drug or a placebo for up to 104 weeks to see if it reduces painful l…

This early-stage trial tests a new drug called HB0043 in 15 adults with moderate to severe hidradenitis suppurativa (HS), a painful skin condition that causes boils and abscesses. The drug targets two inflammatory proteins to potentially control the disease. The main goal is to c…

This study tests a new drug, LAD191, in 200 adults with moderate-to-severe hidradenitis suppurativa (HS), a painful skin condition that causes boils and tunnels under the skin. The goal is to see if LAD191 can reduce the number of inflamed lesions better than a placebo. Participa…

This study monitors the safety and effectiveness of the drug Cosentyx in Korean patients with three conditions: hidradenitis suppurativa (painful skin boils), pediatric plaque psoriasis (scaly skin patches in children), and juvenile idiopathic arthritis (childhood arthritis). Abo…

This study tests a new oral drug, zasocitinib, for moderate to severe hidradenitis suppurativa (HS), a skin condition causing painful, deep bumps and abscesses. About 90 adults will receive either the drug or a placebo for 4 months, then all will get the drug for up to 8 more mon…

This study tests a drug called bimekizumab in children and teenagers (ages 9 to 17) with moderate to severe hidradenitis suppurativa, a painful skin condition that causes boils. The goal is to see how the drug works in the body and if it is safe. About 40 participants will receiv…

This study tests a cream called ruxolitinib for people with mild to moderate hidradenitis suppurativa (HS), a condition that causes painful bumps under the skin. About 550 adults with HS for at least 6 months will apply the cream or a placebo twice daily. The main goal is to see …

This study tests two doses of a drug called remibrutinib against a placebo in 555 people aged 12 and older with moderate to severe hidradenitis suppurativa (HS), a condition causing painful lumps under the skin. The main goal is to see if the drug reduces the number of inflamed n…

This study tests a new drug called brivekimig for people with moderate to severe hidradenitis suppurativa, a chronic skin condition causing painful lumps. About 208 adults will receive either brivekimig or a placebo to see if it reduces skin abscesses and inflammation. The goal i…

This study tests whether injecting botulinum toxin (Botox) into skin lesions can reduce inflammation and pain in people with hidradenitis suppurativa, a chronic skin condition. Researchers believe blocking nerve signals may calm the immune response. The study will enroll 20 adult…

This early-stage study tests a cream called ruxolitinib on 24 people with hidradenitis suppurativa, a painful skin condition. The main goal is to check safety and side effects, not to cure the disease. Participants must have moderate to severe symptoms covering at least 20% of th…

This study is testing a topical foam called roflumilast for people with hidradenitis suppurativa (HS), a painful skin condition. The foam is used alone for mild cases or added to other treatments for moderate to severe cases. The goal is to see if it safely reduces symptoms and i…

This study tests a cream called ruxolitinib for people with mild to moderate hidradenitis suppurativa (HS), a condition that causes painful bumps under the skin. About 550 adults with HS will use either the cream or a placebo for several weeks. The goal is to see if the cream red…

This study tests an investigational drug called lutikizumab for people with moderate to severe hidradenitis suppurativa (HS), a chronic skin disease causing painful lumps and scars. About 1,280 adults and teens will receive either lutikizumab or a placebo for 16 weeks, then all w…

This study is creating a large registry of 3000 people with hidradenitis suppurativa (HS), a painful and poorly understood skin condition. Researchers will collect medical information and blood samples over time to learn what causes HS and how it progresses. The goal is to develo…

This study collects skin samples from 175 people with hidradenitis suppurativa, a painful inflammatory skin disease. The samples are stored in a biorepository for future research. The goal is to help scientists better understand and potentially find new treatments for this and ot…

This study aims to understand how alopecia areata, vitiligo, and hidradenitis suppurativa affect the daily lives and well-being of teens and adults. Researchers will collect information from nearly 2,800 participants across multiple countries using questionnaires and skin assessm…

This study aims to learn more about hidradenitis suppurativa (HS), a painful and poorly understood skin condition. Researchers will follow 1,000 people with HS to track their symptoms, genetics, and other health markers. No new treatments are being tested; instead, the goal is to…

This study collects skin samples from people with conditions like acne, eczema, and psoriasis, as well as healthy volunteers. The goal is to analyze genes and other markers to better understand what causes these inflammatory skin diseases. No treatment is given; it is purely for …

This study looks at how much of the drug bimekizumab ends up in the breast milk of mothers who are already taking it for conditions like psoriasis or arthritis. About 20 breastfeeding women will provide milk samples over several weeks. The goal is to understand possible exposure …

This study is observing 800 adults who are having soft tissue reconstruction surgery using Myriad™, a material made from sheep tissue. The goal is to track safety and how quickly wounds heal. It is not testing a new treatment, but rather collecting real-world data on outcomes and…