New drug brivekimig aims to tame painful skin abscesses in hidradenitis suppurativa

NCT ID NCT07170917

Recruiting now Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 study tests brivekimig, an injected drug, in 208 people with moderate to severe hidradenitis suppurativa (HS), a chronic skin condition causing painful abscesses and tunnels. Participants receive different doses of brivekimig or a placebo for up to 48 weeks. The main goal is to see if brivekimig can reduce abscess and inflammation counts by at least 75%.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

brivekimig (a drug injected under the skin)

What this could lead to

If it works, this could point toward a new treatment option that reduces painful abscesses and inflammation in people with moderate to severe hidradenitis suppurativa.

What could go wrong

This is an early Phase 2 trial with only 208 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hidradenitis suppurativa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIDRADENITIS SUPPURATIVA

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AMR Clinical South Strand, South Carolina- Site Number : 8400018
RECRUITING

Myrtle Beach, South Carolina, 29588, United States
Advanced Medical Research - Atlanta- Site Number : 8400011
RECRUITING

Atlanta, Georgia, 30342, United States
Alfred Hospital - Site Number: 0360002
RECRUITING

Melbourne, Victoria, 3004, Australia
Alpine Research Association- Site Number : 8400008
RECRUITING

Layton, Utah, 84041, United States
Clinical Partners- Site Number : 8400002
RECRUITING

Johnston, Rhode Island, 02919, United States
FXM Clinical Research - Miami- Site Number : 8400017
RECRUITING

Miami, Florida, 33175, United States
FXM Clinical Research - Miramar- Site Number : 8400004
RECRUITING

Miramar, Florida, 33027, United States
Georgia Skin & Cancer Clinic- Site Number : 8400009
RECRUITING

Savannah, Georgia, 31419, United States
Grupo Dermatologico de Carolina- Site Number : 8400023
RECRUITING

Carolina, 00985, Puerto Rico
Interior Dermatology Centre - Site Number: 1240003
RECRUITING

Kelowna, British Columbia, V1W 4V5, Canada
Investigational Site Number : 1240008
RECRUITING

Edmonton, Alberta, T6H 4J8, Canada
Investigational Site Number : 1240009
RECRUITING

Toronto, Ontario, M4E 1R7, Canada
Investigational Site Number : 1560001
RECRUITING

Guangzhou, 510018, China
Investigational Site Number : 1560002
RECRUITING

Chengdu, 610041, China
Investigational Site Number : 1560004
RECRUITING

Shanghai, 200040, China
Investigational Site Number : 1560005
RECRUITING

Ürümqi, 830001, China
Investigational Site Number : 2500002
RECRUITING

Lyon, 69003, France
Investigational Site Number : 2500003
RECRUITING

Bordeaux, 33000, France
Investigational Site Number : 2500006
RECRUITING

Saint-Priest-en-Jarez, 42270, France
Investigational Site Number : 2760001
RECRUITING

Münster, 48149, Germany
Investigational Site Number : 2760002
RECRUITING

Bochum, 44791, Germany
Investigational Site Number : 2760003
RECRUITING

Frankfurt, 60590, Germany
Investigational Site Number : 2760004
RECRUITING

Mainz, 55131, Germany
Investigational Site Number : 2760005
RECRUITING

Kiel, 24105, Germany
Investigational Site Number : 2760006
RECRUITING

Würzburg, 97080, Germany
Investigational Site Number : 2760008
RECRUITING

Bramsche, 49565, Germany
Investigational Site Number : 3000001
RECRUITING

Athens, 16121, Greece
Investigational Site Number : 3000002
RECRUITING

Athens, 124 62, Greece
Investigational Site Number : 3000004
RECRUITING

Thessaloniki, 564 29, Greece
Investigational Site Number : 3000005
RECRUITING

Athens, 16121, Greece
Investigational Site Number : 3480004
RECRUITING

Székesfehérvár, 8000, Hungary
Investigational Site Number : 3760003
RECRUITING

Haifa, 3109601, Israel
Investigational Site Number : 3800001
RECRUITING

Catania, 95123, Italy
Investigational Site Number : 5280002
RECRUITING

Groningen, 9713 GR, Netherlands
Investigational Site Number : 7240007
RECRUITING

Granada, 18014, Spain
Investigational Site Number : 7840001
RECRUITING

Abu Dhabi, 4167, United Arab Emirates
Investigational Site Number : 8260006
RECRUITING

Leeds, LS9 7TF, United Kingdom
Investigational Site Number : 8260008
RECRUITING

London, England, E1 1BB, United Kingdom
Investigational Site Number: 0360001
RECRUITING

Liverpool, New South Wales, 2170, Australia
Investigational Site Number: 1240005
RECRUITING

Québec, Quebec, G1W 4R4, Canada
Investigational Site Number: 1520001
RECRUITING

Santiago, Reg Metropolitana de Santiago, 8380465, Chile
Investigational Site Number: 1520002
RECRUITING

Santiago, Reg Metropolitana de Santiago, 7640881, Chile
Investigational Site Number: 1520003
RECRUITING

Santiago, Reg Metropolitana de Santiago, 7580206, Chile
Investigational Site Number: 1520005
RECRUITING

Santiago, Reg Metropolitana de Santiago, 8420383, Chile
Investigational Site Number: 2030001
RECRUITING

Prague, 110 00, Czechia
Investigational Site Number: 2030002
RECRUITING

Ostrava, 702 00, Czechia
Investigational Site Number: 2030003
RECRUITING

Ostrava, 708 52, Czechia
Investigational Site Number: 2030004
RECRUITING

Prague, 150 06, Czechia
Investigational Site Number: 2500001
RECRUITING

Antony, 92160, France
Investigational Site Number: 2500004
RECRUITING

Bezannes, 51430, France
Investigational Site Number: 2500007
RECRUITING

Toulouse, 31059, France
Investigational Site Number: 3480003
RECRUITING

Pécs, 7632, Hungary
Investigational Site Number: 3760001
RECRUITING

Tel Aviv, 6423906, Israel
Investigational Site Number: 3760002
RECRUITING

Jerusalem, 9112001, Israel
Investigational Site Number: 3800002
RECRUITING

Milan, Milano, 20122, Italy
Investigational Site Number: 6160001
RECRUITING

Wroclaw, Lower Silesian Voivodeship, 50-566, Poland
Investigational Site Number: 6160002
RECRUITING

Warsaw, Masovian Voivodeship, 02-507, Poland
Investigational Site Number: 6160003
RECRUITING

Lodz, Lódzkie, 90-265, Poland
Investigational Site Number: 7240001
RECRUITING

Madrid, 28046, Spain
Investigational Site Number: 7240002
RECRUITING

Manises, Valencia, 46940, Spain
Investigational Site Number: 7240003
RECRUITING

Las Palmas de Gran Canaria, Las Palmas, 35010, Spain
Investigational Site Number: 7240004
RECRUITING

Cadiz, 11009, Spain
Investigational Site Number: 7240005
RECRUITING

Madrid, 28007, Spain
Investigational Site Number: 7240006
RECRUITING

Santiago de Compostela, A Coruña [La Coruña], 15706, Spain
Istituto Dermatologico San Gallicano, IRCCS - Site Number : 3800004
RECRUITING

Roma, 00144, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
JDR Dermatology Research - Site number: 8400012
RECRUITING

Las Vegas, Nevada, 89145, United States
Lima's Excellence in Allergy and Dermatology Research (LEADER) Inc.
RECRUITING

Hamilton, Ontario, L8L 3C3, Canada
Louisiana Dermatology Associates- Site Number : 8400006
RECRUITING

Baton Rouge, Louisiana, 70809, United States
Mayo Clinic in Arizona - Scottsdale- Site Number : 8400014
RECRUITING

Scottsdale, Arizona, 85259, United States
Medical Dermatology Specialists - Site Number: 8400019
RECRUITING

Phoenix, Arizona, 85006, United States
Meiwa Hospital
RECRUITING

Nishinomiya, Hyōgo, 663-8186, Japan
Nihon University Itabashi Hospital
RECRUITING

Tokyo, 173-8610, Japan
Northridge Clinical Trials - Northridge- Site Number : 8400005
RECRUITING

Northridge, California, 91325, United States
Park Dermatology - Site number: 1240007
RECRUITING

Sherwood Park, T8H 0P1, Canada
Site Number: 3480001
RECRUITING

Debrecen, Gangwon-do, 4032, Hungary
The Iowa Clinic West Des Moines Campus- Site Number : 8400007
RECRUITING

West Des Moines, Iowa, 50266, United States
UT Southwestern Medical Center, Department of Dermatology- Site Number : 8400022
RECRUITING

Dallas, Texas, 75235, United States
University of the Ryukyus Hospital - Site Number: 3920002
RECRUITING

Nishihara, Okinawa, 903-0215, Japan
Washington University- Site Number : 8400010
RECRUITING

St Louis, Missouri, 63110, United States