New hope for HS sufferers: LAD191 enters Mid-Stage trial
NCT ID NCT07151937
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new injectable drug called LAD191 in 200 adults with moderate-to-severe hidradenitis suppurativa (HS), a painful skin condition causing abscesses and scarring. Participants will receive either LAD191, a placebo, or an active comparator (adalimumab) to see if LAD191 reduces skin lesions by at least 50% over 16 weeks. The goal is to find a more effective treatment for HS.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- LAD191 (injected under the skin)
- What this could lead to
- If successful, LAD191 could offer a new treatment option to reduce painful abscesses and nodules in people with hidradenitis suppurativa.
- What could go wrong
- This is an early Phase 2 study with only 200 participants. The drug may not work better than placebo, and side effects are still being evaluated.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital de Manises
RECRUITINGManises, 46940, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Head-to-Head: which pill tames hidradenitis suppurativa best?
- Skin disease evolution under the microscope: a 17-Year look at what drives severity
- Could early treatment tame a painful skin condition?
- New pill shows promise for controlling painful skin condition in long-term trial
- New shot could ease painful skin condition