New cream could ease painful skin condition
NCT ID NCT07049575
First seen Jun 26, 2026 · Last updated Aug 07, 2026 · Updated 7 times
Summary
This early-stage trial tests a cream called ruxolitinib on people with hidradenitis suppurativa, a condition causing painful lumps under the skin. The study includes 24 adults and teens and focuses on safety and how much of the drug gets into the body. Participants apply the cream twice daily to affected areas.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ruxolitinib cream
- What this could lead to
- If it works, this could point toward a topical treatment for hidradenitis suppurativa, reducing painful lumps without systemic drugs.
- What could go wrong
- This is a very early Phase 1 trial with only 24 people, focused on safety and drug levels, not yet on effectiveness. It may not lead to a proven treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Amicis Research Center Valencia
RECRUITINGNorthridge, California, 91324, United States
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Centricity Research Columbus
COMPLETEDColumbus, Ohio, 43213, United States
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Children'S Hospital of Orange County
RECRUITINGOrange, California, 92868, United States
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Clarity Dermatology
RECRUITINGCastle Rock, Colorado, 80109, United States
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Clinical Trials Research Institute
RECRUITINGThousand Oaks, California, 91320, United States
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Delricht Research
RECRUITINGBaton Rouge, Louisiana, 70809, United States
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Dr Bobby Buka, Md Greenwich Village
RECRUITINGNew York, New York, 10012-1354, United States
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Equity Medical, Llc
RECRUITINGBowling Green, Kentucky, 42104, United States
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Equity Medical, Llc
RECRUITINGNew York, New York, 10019, United States
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First Oc Dermatology
COMPLETEDFountain Valley, California, 92708, United States
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International Clinical Research Tennessee Llc
RECRUITINGSanford, Florida, 32771, United States
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Lane Dermatology and Dermatologic Surgery
RECRUITINGColumbus, Georgia, 31904, United States
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Lenus Research Medical Group, Llc
RECRUITINGSweetwater, Florida, 33172, United States
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Options Research Group, Llc
RECRUITINGWest Lafayette, Indiana, 47906, United States
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Paddington Testing Co Inc
RECRUITINGPhiladelphia, Pennsylvania, 19103, United States
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Red River Research Partners
RECRUITINGBolivar, Missouri, 65613, United States
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Red River Research Partners
RECRUITINGFargo, North Dakota, 58103, United States
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Revival Research Institute, Llc Troy
RECRUITINGTroy, Michigan, 48084, United States
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Saguaro Dermatology
RECRUITINGPhoenix, Arizona, 85008, United States
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Trueblue Clinical Research
RECRUITINGTampa, Florida, 33609, United States
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Unity Clinical Research
RECRUITINGOklahoma City, Oklahoma, 73118, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could childhood trauma fuel skin inflammation?
- Head-to-Head: which pill tames hidradenitis suppurativa best?
- Skin disease evolution under the microscope: a 17-Year look at what drives severity
- Could early treatment tame a painful skin condition?
- New pill shows promise for controlling painful skin condition in long-term trial
- New shot could ease painful skin condition