New hope for painful skin condition: experimental drug aims to reduce abscesses
NCT ID NCT07225569
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study tests an experimental drug called SAR445399 in 144 adults with moderate to severe hidradenitis suppurativa (HS), a painful skin condition that causes abscesses and tunnels under the skin. Participants will receive one of two doses of the drug or a placebo for 32 weeks. The main goal is to see if the drug can reduce the number of abscesses and inflamed bumps by at least 75% without worsening other symptoms.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Advanced Clinical Research Institute- Site Number : 8400021
RECRUITINGTampa, Florida, 33607, United States
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Alliance for Multispeciality Research - Fort Myers- Site Number : 8400007
RECRUITINGFort Myers, Florida, 33912, United States
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Carbon Health - North Hollywood - NoHo West- Site Number : 8400017
RECRUITINGNorth Hollywood, California, 91606, United States
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Centro de Pesquisas da Clínica IBIS- Site Number : 0760001
RECRUITINGSalvador, Estado de Bahia, 41820-020, Brazil
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Cleaver Medical Group Dermatology- Site Number : 8400008
RECRUITINGCumming, Georgia, 30040, United States
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Dermatology Specialists Research (DS Research) - Kentucky- Site Number : 8400026
RECRUITINGLouisville, Kentucky, 40241, United States
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Elligo Health Research/The Woodlands Dermatology Associates- Site Number : 8400020
RECRUITINGThe Woodlands, Texas, 77380, United States
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Encore Medical Research - Hollywood- Site Number : 8400004
RECRUITINGHollywood, Florida, 33024, United States
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Encore Medical Research of Boynton Beach- Site Number : 8400005
RECRUITINGBoynton Beach, Florida, 33436, United States
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Equity Medical- Site Number : 8400010
RECRUITINGNew York, New York, 10023, United States
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Essential Medical Research- Site Number : 8400015
RECRUITINGOverland Park, Kansas, 66213, United States
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FXM Clinical Research - Fort Lauderdale- Site Number : 8400013
RECRUITINGFort Lauderdale, Florida, 33308, United States
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First Georgia Physician Group- Site Number : 8400033
RECRUITINGFayetteville, Georgia, 30214, United States
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Florida International Research Center- Site Number : 8400002
RECRUITINGMiami, Florida, 33173, United States
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Florida Research Center- Site Number : 8400009
RECRUITINGMiami, Florida, 33174, United States
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Fxm Clinical Research/Fax Pharma Clinical Research- Site Number : 8400014
RECRUITINGMiami, Florida, 33146, United States
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Investigational Site Number : 0320001
RECRUITINGBuenos Aires, 1023, Argentina
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Investigational Site Number : 0320002
RECRUITINGBuenos Aires, 1061, Argentina
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Investigational Site Number : 0360001
RECRUITINGSydney, New South Wales, 2010, Australia
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Investigational Site Number : 0560001
RECRUITINGGhent, 9000, Belgium
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Investigational Site Number : 0560002
RECRUITINGBrussels, 1070, Belgium
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Investigational Site Number : 0560004
RECRUITINGLiège, 4000, Belgium
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Investigational Site Number : 1240002
RECRUITINGSherbrooke, Quebec, J1G 1X9, Canada
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Investigational Site Number : 1240010
RECRUITINGMontreal, Quebec, H1Y 3L1, Canada
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Investigational Site Number : 1240011
RECRUITINGSaskatoon, Saskatchewan, S7K 0H6, Canada
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Investigational Site Number : 1240013
RECRUITINGRegina, Saskatchewan, S4V 1R9, Canada
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Investigational Site Number : 1240014
RECRUITINGToronto, Ontario, M2N 3A6, Canada
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Investigational Site Number : 1560001
RECRUITINGBeijing, 100730, China
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Investigational Site Number : 1560002
RECRUITINGWuhan, 430022, China
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Investigational Site Number : 1560003
RECRUITINGChangsha, 410011, China
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Investigational Site Number : 1560004
RECRUITINGShanghai, 200040, China
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Investigational Site Number : 2500002
RECRUITINGNantes, 44093, France
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Investigational Site Number : 2500003
RECRUITINGRouen, 76031, France
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Investigational Site Number : 2500004
RECRUITINGParis, 75010, France
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Investigational Site Number : 2500005
RECRUITINGLille, 59020, France
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Investigational Site Number : 2500006
RECRUITINGLille, 59037, France
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Investigational Site Number : 2760002
RECRUITINGRostock, 18055, Germany
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Investigational Site Number : 2760003
RECRUITINGRegensburg, 93053, Germany
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Investigational Site Number : 2760004
RECRUITINGBlankenfelde-Mahlow, 15831, Germany
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Investigational Site Number : 2760005
RECRUITINGMerzig, 66663, Germany
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Investigational Site Number : 2760007
RECRUITINGDarmstadt, 64283, Germany
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Investigational Site Number : 3480002
RECRUITINGBudapest, 1085, Hungary
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Investigational Site Number : 3480003
RECRUITINGKaposvár, 7400, Hungary
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Investigational Site Number : 3480004
RECRUITINGSzeged, 6720, Hungary
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Investigational Site Number : 3480005
RECRUITINGGyula, 5700, Hungary
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Investigational Site Number : 3800001
RECRUITINGChieti, 66100, Italy
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Investigational Site Number : 3800002
RECRUITINGTorette, Ancona, 60020, Italy
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Investigational Site Number : 3800003
RECRUITINGMilan, Milano, 20132, Italy
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Investigational Site Number : 3800004
RECRUITINGBrescia, 25123, Italy
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Investigational Site Number : 3800005
RECRUITINGCona, Ferrara, 44124, Italy
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Investigational Site Number : 3920001
RECRUITINGTokyo, 173-8610, Japan
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Investigational Site Number : 3920002
RECRUITINGTokyo, 160-0023, Japan
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Investigational Site Number : 7240001
RECRUITINGCórdoba, 14004, Spain
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Investigational Site Number : 7240002
RECRUITINGBilbao, Basque Country, 48013, Spain
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Investigational Site Number : 7240004
RECRUITINGMálaga, 29016, Spain
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Investigational Site Number : 7240005
RECRUITINGSeville, Sevilla, 41009, Spain
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Investigational Site Number : 7240006
RECRUITINGBarcelona, Barcelona [Barcelona], 08035, Spain
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Investigational Site Number : 7520001
RECRUITINGÖrebro, 701 85, Sweden
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Investigational Site Number : 7520002
RECRUITINGUppsala, 752 37, Sweden
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Investigational Site Number : 7920001
RECRUITINGIstanbul, 34093, Turkey (Türkiye)
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Investigational Site Number : 7920002
RECRUITINGManisa, 45030, Turkey (Türkiye)
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Investigational Site Number : 7920003
RECRUITINGSamsun, 55139, Turkey (Türkiye)
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Investigational Site Number : 7920004
RECRUITINGIzmir, 35540, Turkey (Türkiye)
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Investigational Site Number : 7920005
RECRUITINGIstanbul, 34899, Turkey (Türkiye)
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Investigational Site Number : 7920006
RECRUITINGBuca, 35390, Turkey (Türkiye)
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Scottsdale Clinical Trials- Site Number : 8400006
RECRUITINGScottsdale, Arizona, 85260, United States